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Isolation and Molecular Characterization of Acanthamoeba Strains from Dental Units in Costa Rica
(2015-03)Free-living amoebae are protozoa widely distributed in nature, which can be found in a variety of environments. Four genera are recognized as causal agents of infections in humans and animals: Acanthamoeba, Naegleria, Balam ... -
Isolation and partial characterization of a myotoxin from the venom of the snake Bothrops nummifer
(1986)A myotoxin from the venom of the snake Bothrops nummifer was purified to homogeneity by ion-exchange chromatography on CM-Sephadex. The toxin is a basic dimer with a subunit molecular weight of 16,000, as estimated by ... -
Isolation from a polyvalent antivenom of antibodies to a myotoxin in Bothrops asper snake venom
(1985)Antibodies against Bothrops asper rmyotoxin were purified from a polyvalent antivenom by affinity chromatography . These antibodies neutralized most of the myotoxic activity of crude B. asper venom, as judged by histologic ... -
Isolation of a galactose-binding lectin from the venom of the snake Bothrops godmani (Godmann's pit viper).
(1990)A galactose-binding lectin, isolated from the venom of B. gotlmani by affinity chromatography . is an acidic protein (pI 4.9) with a subunit mol. wt of about 14,000, occurring mostly as a disulfide-linked dimer of 28,000. ... -
Isolation of a Toxigenic and Clinical Genotype of Clostridium difficile in Retail Meats in Costa Rica
(2013-02)We isolated a regional toxigenic genotype of Clostridium difficile, previously found in human infection in 4 of 200 (2%) samples of retail meats for human consumption: 1 of 67 samples of beef, 2 of 66 of pork, and 1 of 67 ... -
Isolation of Acanthamoeba T5 from Water: Characterization of Its Pathogenic Potential, Including the Production of Extracellular Vesicles
(2020-01-23)Acanthamoeba is a genus of free-living amoebae widely distributed in nature, associated with the development of encephalitis and keratitis. Despite the fact that it is common to find genotype T5 in environmental samples, ... -
Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: Biochemical and toxicological characterization
(2010-03)Phospholipases A2 (PLA2) are major components of snake venoms, exerting a variety of relevant toxic actions such as neurotoxicity and myotoxicity, among others. Since the majority of toxic PLA2s are basic proteins, acidic ... -
Isolation of basic myotoxins from Bothrops Moojeni and Bothrops Atrox snake venoms
(1990)Three myotoxins, one from the venom of Bothrops atrox and two from the venom of B. moojeni, were isolated by ion-exchange chromatography on CM-Sephadex C-25. The three toxins are basic proteins with an estimated mol. wt ... -
Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: comparative characterization and synergism between Asp49 and Lys49 variants
(2019)Bothrops diporus, previously considered a subspecies of the B. neuwiedi complex, is a medically relevant viperid in Northeastern Argentina. The venom of this species causes local tissue damage characterized by ... -
Isolation, characterization and molecular cloning of AnMIP, a new α-type phospholipase A2 myotoxin inhibitor from the plasma of the snake Atropoides nummifer (Viperidae: Crotalinae)
(2007)A new phospholipase A2 (PLA2)-inhibitory protein was isolated from the plasma of Atropoides nummifer, a crotaline snake from Central America. This inhibitor was named AnMIP, given its ability to neutralize the activity ... -
Isquemia mesentérica aguda: revisión de tema y propuesta de protocolo de manejo en el servicio de vascular periférico del Hospital Rafael Ángel Calderón Guardia
(2020-07-20)La isquemia mesentérica aguda es una patología poco frecuente, pero de alta mortalidad. Las cuatro principales causas son: el embolismo arterial, la trombosis arterial, la isquemia mesentérica no oclusiva, y la trombosis ... -
Íleo biliar, un desafío para el cirujano
(2020-08-04)El íleo biliar es una complicación rara de la colelitiasis. Esta patología ocurre como resultado de una fístula bilioentérica debido a la erosión del lito en la vesícula. Esta enfermedad se presenta más comúnmente en ... -
El índice leucoglicémico como factor pronóstico y de morbimortalidad en infarto agudo de miocardio en pacientes infartados de Hospital Calderón Guardia de la Caja Costarricense del Seguro social en el periodo de julio del 2019 a junio 2020
(2021)Introducción: En Costa Rica, así como en el mundo industrializado, la principal causa de muerte es el infarto agudo de miocardio, ocupando el primer lugar de las causas de defunciones en el 2018, por lo que se hace primordial ... -
Índices bibliométricos y revistas de ‘corriente central’: implicaciones para el desarrollo de las ciencias naturales en Costa Rica
(2015)Dada esta amplia variación en la calidad de las publicaciones en ciencias naturales, es esencial para la comunidad científica tener una perspectiva clara de dicha heterogeneidad y de sus implicaciones ... -
JADE: proyecto de desarrollo integral dirigido a personas adultas con discapacidad intelectual y su influencia en la condición higiénica oral
(2021)La población con discapacidad, según numerosos reportes, exhibe deficientes condiciones de salud oral si se le compara con el resto de la población. Esta realidad se ve agravada cuando se considera a las personas adultas ... -
Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases
(2011-08-24)Hemorrhage is one of the most significant effects in envenomings induced by viperid snakebites. Damage to the microvasculature, induced by snake venom metalloproteinases (SVMPs), is the main event responsible for this ... -
KI 67 como factor pronóstico de recurrencia después de radioterapia adyuvante en pacientes con cáncer de mama temprano en el Hospital México del 01 de enero del 2010 al 31 de diciembre del 2011
(2021-03-10)El objetivo principal del estudio es determinar si el Ki67 muestra algún valor pronóstico para el tiempo de recurrencia en las pacientes con carcinoma de mama estadio clínico temprano que recibieron adyuvancia con radioterapia ... -
Knock-down of synapsin alters cell excitability and action potential waveform by potentiating BK and voltage-gated Ca2+ currents in Helix serotonergic neurons
(2015)Synapsins (Syns) are an evolutionarily conserved family of presynaptic proteins crucial for the fine-tuning of synaptic function. A large amount of experimental evidences has shown that Syns are involved in the ...