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Pericarditis infecciosa en niños: experiencia del Hospital de Niños de Costa Rica a través de 20 años
(2022)Introducción: La pericarditis infecciosa es la inflamación del pericardio de etiología infecciosa, siendo una de las causas de derrame pericárdico en niños, aun así los estudios en la población pediátrica son limitados. ... -
La perspectiva de los actores sociales involucrados sobre la Red de Atención Progresiva para el Cuido Integral de la Persona Adulta Mayor. Costa Rica, 2011-2021
(2021)El estudio acerca de “La perspectiva de los actores sociales involucrados sobre la Red de Atención Progresiva para el Cuido Integral de la Persona Adulta Mayor de Costa Rica en el periodo 2011 al 2021, buscó comprender el ... -
Perspectiva epidemiológica control, prevención e investigación de la diarrea en Costa Rica
(Rev. Méd. Hosp. Nac. Niños, Costa Rica, 15 (1), 1980, 1980)La primera parte del trabajo describe el marcado descenso en la mortalidad por diarreas que se inició en la década de 1940, y que después de un período de estancamiento durante el lapso 1948-64, descendió hasta la baja ... -
La pertinencia de las ciencias sociales, en la investigación y la educación en salud, desde una mirada cualitativa
(2018-09)En el marco de la teoría de los intereses constitutivos de saberes de Habermas, las ciencias de la salud no han sido posicionadas, de manera formal en ella para explicar, comprender y transformar sus objetos o fenómenos ... -
Perturbation-Based Modeling Unveils the Autophagic Modulation of Chemosensitivity and Immunogenicity in Breast Cancer Cells
(2021-09-18)In the absence of new therapeutic strategies, chemotherapeutic drugs are the most widely used strategy against metastatic breast cancer, in spite of eliciting multiple adverse effects and having low responses with an ... -
Pesticide occurrence and water quality assessment from an agriculturally influenced Latin-American tropical region
(2021-01)A monitoring study was carried out in three agriculturally influenced microcatchments in Costa Rica during 2012e2014, for pesticides and water quality parameters. A total of 42 pesticides were analyzed, detecting the ... -
PET/CT con F18-FDG en población infantojuvenil con diagnóstico de LInfoma. Experiencia del Servicio de Medicina Nuclear de la Pontificia Universidad Católica de Chile - Red de Salud UC Christus entre enero 2009 a junio 2019
(2021-02-08)Objetivo: el objetivo de esta investigación fue describir la experiencia en el uso del PET/CT con F18-FDG como herramienta imagenológica en población infantojuvenil con diagnóstico de linfoma Metodología: de forma ... -
Pénfigo vulgar y su manejo integral: Reporte de dos casos y revisión de literatura
(2021-04-15)En la cavidad oral se pueden presentar lesiones en gíngiva que no están asociadas a placa bacteriana, las cuales requieren de un adecuado diagnóstico y tratamiento. La gingivitis descamativa está usualmente relacionada con ... -
Pharmaceutical assistance programs to support smoking cessation medication access
(2017-11-03)OBJECTIVES: Rural smokers are more likely to be uninsured and live in poverty, which may pose significant cost barriers to accessing smoking cessation medications. As part of a randomized clinical trial, we provided support ... -
Pharmacokinetic-pharmacodynamic relationships of immunoglobulin therapy for envenomation.
(2003-07)Parenteral administration of horse- and sheep-derived antivenoms constitutes the cornerstone in the therapy of envenomations induced by animal bites and stings. Depending on the type of neutralising molecule, antivenoms ... -
Pharmacokinetics of whole IgG equine antivenom: comparison between normal and envenomed rabbits
(2006-09-01)Pharmacokinetics of antivenoms has been mainly studied in normal animals, whereas very little is known on pharmacokinetics in envenomed animals. The aim of this study was to compare pharmacokinetic parameters of whole IgG ... -
Pharmacological modulation of edema induced by Lys-49 and Asp-49 myotoxic phospholipases A2 isolated from the venom of the snake Bothrops asper (terciopelo)
(1998-12)The pharmacological modulation of edema-forming activity of Bothrops asper myotoxins II and III, Lys-49 and Asp-49 phospholipases A2, respectively, was studied plethysmographically in the mouse foot pad model. Myotoxin III ... -
Pharmacological modulation of hyperalgesia induced by Bothrops asper (terciopelo) snake venom
(2001-08)The ability of Bothrops asper snake venom to cause hyperalgesia was investigated in rats, using the paw pressure test. Intraplantar injection of the venom (5–15 μg/paw) caused a dose and time-related hyperalgesia, which ... -
Pharmacological study of edema induced by venom of the snake Bothrops asper (terciopelo) in mice
(1995-01)The effect of several drugs on the edema-forming activity of Bothrops asper venom was studied plethysmographically using the mouse foot pad assay. Bothrops asper venom induced a dose-dependent edema which developed rapidly ... -
Phenotype in Psychiatric Genetic Research
(2012-01-05)Mental illnesses differ from medical conditions in their lack of objectively assessable biological markers for the establishment of a diagnosis. In the absence of clear external validators such as laboratory tests or ... -
Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS are differentially impacted by BvrR phosphorylation
(2023-04)Brucella abortus is a zoonotic pathogen whose virulence depends on its ability to survive intracellularly at the endoplasmic reticulum derived compartment. The two-component system BvrR/BvrS (BvrRS) is essential for ... -
Phenotypic and Genotypic Characterization of Multidrug-Resistant Bacteroides, Parabacteroides spp., and Pseudoflavonifractor from a Costa Rican Hospital
(2014-09)Multidrug resistance in Bacteroides spp. and related genera is uncommon and has not been described in Latin America until now. We studied phenotypically and genotypically the multidrug resistance of 10 clinical strains of ... -
Phenotypic identification of over 1000 isolates of anaerobic bacteria recovered between 1999 and 2008 in a major Costa Rican hospital
(2011-07)Because of limitations in infrastructure, the aetiology of infections caused by anaerobic bacteria is seldom determined in clinical laboratories of developing countries. This study reports on the identification of 1010 ... -
Phenylketonuria in Costa Rica: preliminary spectrum of PAH mutations and their associations with highly polymorphic haplotypes
(1996)A preliminary evaluation of the molecular basis of phenylketonuria (PKU) in Costa Rica was made by performing mutational analyses in the six PKU families identified to date. These studies revealed the presence of the ...