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Assessing endotoxins in equine-derived snake antivenoms: Comparison of the USP pyrogen test and the Limulus Amoebocyte Lysate assay (LAL)
(2015-08-29)Snake antivenoms are parenterally administered; therefore, endotoxin content must be strictly controlled. Following international indications to calculate endotoxin limits, it was determined that antivenom doses between ... -
Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics
(2013-07)The assessment of the capacity of antivenoms to neutralize the lethal activity of snake venoms is the gold standard in the preclinical analysis of antivenom efficacy, and is routinely performed by manufacturers and quality ... -
Assessment of acute toxicity of carbofuran in Macrobrachium olfersii (Wiegmann, 1836) at different temperature levels
(2013-07-11)Carbofuran (2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate; C12H15NO3) is one of the most toxic carbamate pesticides. For acute toxicity of carbofuran, juveniles of Macrobrachium olfersii were exposed to different ... -
Assessment of metalloproteinase inhibitors clodronate and doxycycline in the neutralization of hemorrhage and coagulopathy induced by Bothrops asper snake venom
(2008-12-01)Snake venom metalloproteinases (SVMPs) play a prominent role in the local and systemic manifestations of viperid snakebite envenomations. Thus, the possibility of using metalloproteinase inhibitors in the treatment of these ... -
Assessment of microbial communities associated with the gut and feeding substrate of three xylophagous coleopteran families with emphasis on cellulose-degrading bacteria
(2019-11)The current energy crisis and depletion of fossil fuel reserves has encouraged research for new alternatives. Degradation of plant material by enzymatic reactions represents an important strategy to obtain affordable and ... -
Assessment of the viral safety of antivenoms fractionated from equine plasma
(2004-09)Antivenoms are preparations of intact or fragmented (F(ab')2 or Fab) immunoglobulin G (IgG) used in human medicine to treat the severe envenomings resulting from the bites and stings of various animals, such as snakes, ... -
Association between Active Transportation and Public Transportation with an Objectively Measured Meeting of Moderate-To-Vigorous Physical Activity and Daily Steps Guidelines in Adults by Sex from Eight Latin American Countries
(2021)This study aimed to examine the associations between active transportation and public transport and the objectively measured meeting of moderate-to-vigorous physical activity (MVPA) and steps per day guidelines in adults ... -
Association between built environment and physical activity in Latin American countries: a multicentre cross-sectional study
(2021)Abstract Objective: To assess the association between the physical activity level and the built environment by accessibility, microinfrastructure and security in Latin America (LA). Design: We conducted a multicentre ... -
Association between hepatic lipase -514 C/T promoter polymorphism and myocardial infarction is modified by history of hypercholesterolemia and waist circumference
(2009)Background and aims: To examine whether the association between the 514 C/T polymorphism of the hepatic lipase gene and myocardial infarction (MI) is modified by history of hypercholesterolemia and increased waist ... -
Association between Perceived Neighborhood Built Environment and Walking and Cycling for Transport among Inhabitants from Latin America: The ELANS Study
(2020)Purpose: This study aimed to examine the associations of the perceived neighborhood built environment with walking and cycling for transport in inhabitants from Latin American countries. Methods: This cross-sectional ... -
Association of Apolipoprotein E-e4 and Dementia Declines with Age
(2014-10)To study the association of dementia with apolipoprotein E-e4 (APOE-e4) and its interaction with age in a nonagenarian Costa Rican group (N-sample) and a general elderly contrast group (GE-sample). In both case-control ... -
Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer
(2020)Background/aim: Enzymatic variants involved in fluoropyrimidine metabolism have been associated with adverse events (AEs). We assessed the association between C677T (rs1801133) and A1298 (rs1801131) methylenetetrahydrofolate ... -
Association of interleukin-1B and interleukin-1RN polymorphisms with gastric cancer in a high-risk population of Costa Rica
(Clinical and Experimental Medicine 5 p.169-176, 2005-09-13)Several risk factors have been associated with gastric cancer, among them Helicobacter pylori infection. This bacterium yields inflammation, the degree of which depends on the bacterial strain and the severity of the host ... -
Association of moderate-to vigorous physical activity with neck circumference in eigth Latin American countries
(2019)Background: Physical activity is a cornerstone in the prevention and treatment of obesity. There are relatively few studies that explore the effect of accelerometer-determined moderate-to-vigorous physical activity (MVPA) ... -
Association of serum pepsinogen with atrophic body gastritis in Costa Rica
(Clinical and Experimental Medicine 6 p.72-78, 2006-05-26)Abstract Individuals with atrophic gastritis (AG), especially atrophic body gastritis (ABG), are at increased risk of developing gastric cancer. Serum concentrations of pepsinogens (PG) have been proposed as markers for ... -
Associations between urban structure and Aedes aegypti larval habitats in Puntarenas, Costa Rica
(2008-12)Geospatial technologies have been increasingly applied to study vector-borne diseases, although their use in urban setting has been limited. In this study, high-resolution satellite imagery from QuickBird was analyzed to ... -
Ataxias espinocerebelosas de herencia autosómica dominante (SCAs): características, clasificación y diagnóstico
(Neuroeje, Enero-Junio 2012 Volumen 25 (1) 9-19, 2012)The autosomal dominant spinocerebellar ataxias (SCAs, also known as ADCAs) are a group of progressive neurodegenerative diseases characterized by loss of balance and motor coordination, and comprise a highly ... -
Atención farmacéutica: Seguimiento del tratamiento farmacológico
(Centro Nacional de Información de Medicamentos, Facultad de Farmacia, Universidad de Costa Rica, 2003)En el texto se analizan los conceptos de atención farmacéutica y seguimiento farmacoterapéutico; la metodología para dar ese seguimiento y la relación farmacéutico, médico y paciente desde la perspectiva profesional. También ... -
Atresia de Esófago. Actualización en el protocolo del manejo quirúrgico en el Hospital Nacional de Niños, Dr. Carlos Sáenz Herrera
(2023)Este estudio contempla el análisis desde una revisión sistemática de la atresia de esófago ( AE) desde la propuesta de la actualización en el protocolo del manejo quirúrgico en el Hospital Nacional de Niños. La AE es una ...