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Now showing items 1-10 of 1934
Inhibition of the hemorrhagic activity of Bothrops asper venom by a novel neutralizing mixture
(1997-06)
This study screened 25 sera, 19 synthetic products and five antivenoms obtained after immunization for their ability to neutralize the hemorrhagic activity of venom from the snake Bothrops asper. Among the sera screened, ...
Tecnologías de secuenciación de nueva generación: principios, aplicaciones y escenario en Costa Rica
(2017-12)
La secuenciación de nueva generación (NGS, por sus siglas en inglés) corresponde a un grupo de tecnologías originadas a mediados de la década del 2000 por la necesidad de mejorar la capacidad de procesamiento y reducción ...
Effect of calcineurin inhibitors on myotoxic activity of crotoxin and Bothrops asper phospholipase A2 myotoxins in vivo and in vitro
(2006-07)
Previous studies have shown that calcineurin activity plays a critical role in the myotoxic activity induced by crotoxin (CTX), a group II phospholipase A2 (PLA2) with neurotoxic and myotoxic actions. In order to address ...
Snake Venomics of Central American Pitvipers: Clues for Rationalizing the Distinct Envenomation Profiles of Atropoides nummifer and Atropoides picadoi
(2008)
We report the proteomic characterization of the Central American pitvipers Atropoides nummifer and
Atropoides picadoi. The crude venoms were fractionated by reverse-phase high-performance liquid
chromatography (HPLC), ...
Efecto del extracto acuoso de hojas de Licania platypus (Hemsl.) Fritsh. Sobre la protección gástrica y la motilidad gastrointestinal
Effect of leaves aqueous extract of Licania Platypus (Hemsl.) Fritsch. On gastroprotection and gastrointestinal motility
(2018-09-20)
Licania platypus se distribuye ampliamente en países tropicales. Tradicionalmente, en América Central se ha utilizado para diversos problemas de salud, especialmente gastrointestinales. Objetivo: Investigar la actividad ...
Promoción y apoyo de una alimentación complementaria apropiada en el periodo del destete y el uso de recursos locales para este fin
(Revista Médica del Hospital Nacional de Niños Dr. Carlos Sáenz Herrera, 14(1): 53-79. 1979, 1979)
La experiencia acumulada en la última década sobre los factores que favorecen o interfieren el crecimiento y desarrollo normal del niño, permite reconocer que la alimentación juega un papel preponderante. En base a este ...
Trites of class-specific anitbodies against Shigella and Salmonella lipopolysaccharide antigens in colostrums and breast milk of Costa Rican, Swedish and Vietnamese mothers
(1992)
Enzyme immunoassays (El A) were used to estimate titres of class-specific antibodies against purified and chemically defined phenol-water-extracted lipopolysaccharide (LPS) antigens of Salmonella serogroup B (BO), Shigella ...
Pharmacological modulation of hyperalgesia induced by Bothrops asper (terciopelo) snake venom
(2001-08)
The ability of Bothrops asper snake venom to cause hyperalgesia was investigated in rats, using the paw pressure test. Intraplantar injection of the venom (5–15 μg/paw) caused a dose and time-related hyperalgesia, which ...
In vivo neutralization of the dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG monoclonal antibodies
(2018)
The black mamba (Dendroaspis polylepis) is one of the most feared snake species of the
African savanna. It has a potent, fast-acting neurotoxic venom comprised of dendrotoxins and
α-neurotoxins associated with high ...
Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs
(2005-12)
Caprylic acid purification of IgG, currently used in the manufacture of horse-derived antivenoms, was successfully adapted for the preparation of sheep and camel IgG. Sheep IgG had a molecular mass of approximately 150 ...