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dc.creatorLeal Esquivel, Alejandro
dc.creatorEndele, Sabine
dc.creatorStengel, Corinna
dc.creatorHuehe, Kartrin
dc.creatorLoetterle, Joachim
dc.creatorBarrantes Mesén, Ramiro
dc.creatorWinterpacht, Andreas
dc.creatorRautenstrauss, Bernd
dc.date.accessioned2015-07-31T21:17:58Z
dc.date.available2015-07-31T21:17:58Z
dc.date.issued2003-07
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/S0378111903006139
dc.identifier.issn0378-1119
dc.identifier.issn1879-0038
dc.identifier.urihttps://hdl.handle.net/10669/15154
dc.descriptionartículo -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 2003. Este documento es privado debido a limitaciones de derechos de autor.es_ES
dc.description.abstractA human myosin heavy chain gene was identified in chromosome 19q13 by computational sequence analysis, RT-PCR and DNA sequencing of the cDNA. The complete cDNA has a length of 6786 bp and comprises 41 exons (40 coding) included in 108 kb of genomic sequence. Alternative splicing variants were also identified. The gene is expressed in a multitude of tissues, but mainly in small intestine, colon and skeletal muscle. The putative protein (228 kDa) carries the common myosin domains and presents high homology with the nonmuscle myosin heavy chains (MYH9 and MY1410) as well as the smooth muscle myosin heavy chain MYH11. Nevertheless, phylogenetic analysis indicated that these homologous proteins are more related among themselves than to MY1-114, suggesting that possibly this myosin heavy chain should be classified in a new myosin-subfamily.es_ES
dc.description.sponsorshipUniversidad de Costa Rica, Instituto de Investigaciones en Saludes_ES
dc.language.isoen_USes_ES
dc.publisherGene: 312 p. 165-171es_ES
dc.sourceGene 312:165-171es_ES
dc.subjectMYH14es_ES
dc.subjectNon-muscle myosines_ES
dc.subjectcDNA Sequence;es_ES
dc.subjectcolones_ES
dc.subjectSciatic nervees_ES
dc.subjectHuman geneticses_ES
dc.subjectSalud públicaes_ES
dc.titleA novel myosin heavy chain gene in human chromosome 19q13.3es_ES
dc.typeartículo científico
dc.identifier.doi10,101660378-1119(03)00613-9
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES


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