Listar Microbiología por autor "Jenkins, Timothy P."
Mostrando ítems 1-3 de 3
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An interactive database for the investigation of high-density peptide microarray guided interaction patterns and antivenom cross-reactivity
Krause, Kamille E.; Jenkins, Timothy P.; Skaarup, Carina; Engmark, Mikael Mikael Gerling; Casewell, Nicholas R.; Ainsworth, Stuart; Lomonte, Bruno; Fernández Ulate, Julián; Gutiérrez, José María; Lund, Ole; Laustsen, Andreas Hougaard (2020)Snakebite envenoming is a major neglected tropical disease that affects millions of people every year. The only effective treatment against snakebite envenoming consists of unspecified cocktails of polyclonal antibodies ... -
Discovery and optimization of a broadly-neutralizing human antibody against long-chain α-neurotoxins from snakes
Ledsgaard, Line; Wade, Jack; Jenkins, Timothy P.; Boddum, Kim; Oganesyan, Irina; Harrison, Julian A.; Villar, Pedro; Leah, Rachael A.; Zenobi, Renato; Schoffelen, Sanne; Voldborg, Bjørn; Ljungars, Anne; McCafferty, John; Lomonte, Bruno; Gutiérrez, José María; Laustsen, Andreas Hougaard; Karatt Vellatt, Aneesh (2023-02-08)Snakebite envenoming continues to claim many lives across the globe, necessitating the development of improved therapies. To this end, broadly-neutralizing human monoclonal antibodies may possess advantages over current ... -
In vivo neutralization of Myotoxin II, a phospholipase A2 homolog from Bothrops asper venom, using peptides discovered via phage display technology
Laustsen, Andreas Hougaard; Gless, Bengt H.; Jenkins, Timothy P.; Meyhoff Madsen, Maria; Bjärtun, Johanna; Munk, Andreas S.; Oscoz, Saioa; Fernández Ulate, Julián; Gutiérrez, José María; Lomonte, Bruno; Lohse, Brian (2022)Many snake venom toxins cause local tissue damage in prey and victims, which constitutes an important pathology that is challenging to treat with existing antivenoms. One of the notorious toxins that causes such effects ...