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Heterologous hyperimmune polyclonal antibodies against SARS-COV-2: A broad coverage, affordable, and scalable potential immunotherapy for Covid-19
(2021-09)
The emergence and dissemination of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) and the resulting COVID-19 pandemic triggered a global public health crisis.
Although several SARS-CoV-2 vaccines have ...
The Phospholipase A2 Homologues of Snake Venoms: Biological Activities and Their Possible Adaptive Roles
(2009)
A particular subgroup of toxins with phospholipase A2 (PLA2) structure, but devoid of this enzymatic activity, is commonly found in the venoms of snakes of the family Viperidae, and known as the PLA2 homologues. Among ...
Bioavailability of in-feed tetracyclines is influenced to a greater extent by crude protein rather than calcium
(2014-12)
Feed is a common vehicle for tetracycline administration in animal farming. However, veterinarians and farmers often overlook that common feed components, such as proteins and calcium, may interact with these drugs and ...
Blaesoxipha plinthopyga (Diptera: Sarcophagidae) como responsable de miasis nosocomiales en Costa Rica
Blaesoxipha plinthopyga (Diptera: Sarcophagidae) as an agent responsible for nosocomial myiasis in Costa Rica
(2014)
Se presentan dos casos de miasis nosocomiales, ocurridos en hospitales costarricenses, cuyo agente etiológico identificado fue Blaesoxipha plinthopyga (Diptera: Sarcophagidae). El primero tuvo lugar como infestación de una ...
Porphyromonas spp. have an extensive host range in ill and healthy individuals and an unexpected environmental distribution: a systematic review and meta-analysis
(2020-10-01)
Studies on the anaerobic bacteria Porphyromonas, mainly focused on P. gingivalis, have revealed new bacterial structures, metabolic pathways, and physiologic functionalities. Porphyromonas are mainly described as being ...
Métodos de Investigación: destrezas básicas para el trabajo científico en las disciplinas biomédicas
(2020-10-01)
Esta obra didáctica nace con el objetivo de presentar a sus lectores una visión
introductoria sobre el fenómeno científico actual, sus orígenes, su contexto
costarricense, y posteriormente presentar las principales ...
Predicting Cancer Chemosensitivity Based on Intensity/Distribution Profiles of Cells Loaded with a Fluorescent Sphingolipid Analogue
(2018)
Cancer is a group of heterogeneous and complex
diseases, with limited therapeutic options due to the recurrent
emergence of drug resistance. Sphingolipids are bioactive
molecules that participate in signaling of cell ...
Predominance and high antibiotic resistance of the emerging Clostridium difficile genotypes NAPCR1 and NAP9 in a Costa Rican hospital over a 2-year period without outbreaks
(2016-05)
Clostridium difficile is the major causative agent of nosocomial antibiotic-associated diarrhea. In a 2009 outbreak of C. difficileassociated diarrhea that was recorded in a major Costa Rican hospital, the hypervirulent ...
Assessing endotoxins in equine-derived snake antivenoms: Comparison of the USP pyrogen test and the Limulus Amoebocyte Lysate assay (LAL)
(2015-08-29)
Snake antivenoms are parenterally administered; therefore, endotoxin content must be strictly controlled. Following international indications to calculate endotoxin limits, it was determined that
antivenom doses between ...
Situación Actual de Egresos Hospitalarios asociados a Enfermedad de Wilson en Costa Rica
Current Situation of Hospital Discharges associated with Wilson's Disease in Costa Rica
(2019)
La Enfermedad de Wilson (EW) tiene alta incidencia en Costa Rica y existe poca
información epidemiológica publicada al respecto en el país. Este trabajo tiene como objetivo
actualizar la información local de esta enfermedad ...