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Antivenoms for the treatment of snakebite envenomings: The road ahead
(2011-05)
The parenteral administration of antivenoms is the cornerstone of snakebite envenoming therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are available world-wide. We address the main issues ...
Mecanismo de açao dos venenos de cobras corais
(2016)
Os venenos apresentam um importante papel fisiológico para as serpentes: são os fatores responsáveis pela subjugação das presas, iniciam e auxiliam sua digestão e constituem um mecanismo de defesa contra predadores/agressores, ...
Antivenoms for Snakebite Envenomings
(2011-10)
Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming. Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a single or several medically-relevant snake ...
The Need for Full Integration of Snakebite Envenoming within a Global Strategy to Combat the Neglected Tropical Diseases: The Way Forward
(2013-06-13)
Snakebite envenoming constitutes a serious medical condition that primarily affects residents of rural communities in Africa, Asia, Latin America, and New Guinea [1], [2]. It is an occupational, environmental, and domestic ...
Pathological and biochemical changes induced in mice after intramuscular injection of venom from newborn specimens of the snake Bothrops asper (Terciopelo)
(1992-09)
Venom from newborn Bothrops asper snakes has higher lethal, hemorrhagic, edema-forming, proteolytic and defibrinating activities than venom from adult B. asper specimens. Electrophoretic analysis confirmed the variation ...
Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice
(2001-02)
Stings by Thalassophryne nattereri are responsible for envenomation of fishermen in north-eastern Brazil. Its venom induces prominent local tissue damage, characterized by pain, oedema and necrosis. The pathogenesis of ...
Amino acid sequence of a myotoxic Lys49-phospholipase A2 homologue from the venom of Cerrophidion (Bothrops) godmani
(1998-05-19)
The complete amino acid sequence of myotoxin II (godMT-II), a myotoxic phospholipase A2 (PLA2) homologue from the venom of the Central American crotaline snake Cerrophidion (Bothrops) godmani, was determined by direct ...
Calcium plays a key role in the effects induced by a snake venom Lys49 phospholipase A2 homologue on a lymphoblastoid cell line
(2006-01)
A catalytically-inactive Lys49 phospholipase A2 homologue from the venom of the snake Bothrops asper induces diverse effects (necrosis, apoptosis and proliferation) in a lymphoblastoid cell line, depending on the toxin ...
Role of nitric oxide in the local and systemic pathophysiological effects induced by Bothrops asper snake venom in mice
(2006)
Objective
To assess the role of nitric oxide in the most relevant local and systemic manifestations in mice injected with the venom of the snake Bothrops asper. Mice were pretreated with nitric oxide synthase inhibitors, ...
Dissociation of enzymatic and toxic activities by the use of antibodies
Disociación de las actividades enzimáticas y tóxicas mediante la utilización de anticuerpos
(1990)
IN
A
RECENT
article
KASTURi
and
GOWDA,(1990)
described
the
dissociation
of
enzymatic
and
toxic
activities
of
phospholipases
A,
(PLA)
from
Vipera
russelli
venom
by
neutraliza-
tion
experiments
u ...