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Myotoxin-neutralizing peptides
PEPTIDES NEUTRALISANT LES MYOTOXINES
(2018-03-27)
The present invention relates to polypeptides having myotoxin-neutralizing properties and their use for treatment of envenomation. The present invention further relates to methods for neutralizing a venom using the polypeptide ...
Comparison of the adjuvant activity of emulsions with different physicochemical properties on the antibody response towards the venom of West African carpet viper (Echis ocellatus)
(2017)
Adjuvant emulsions are widely used to enhance the antibody response of the animals used as immunoglobulin source for producing antivenoms. Usually, the adjuvant activity of emulsions is attributed both to their ability to ...
Snakebite Envenomingin Latin America and the Caribbean
(2014)
Envenomings induced by snakebites constitute a serious public health problem in Latin America. This condition affects predominantly vulnerable rural populations and has a high impact in regions where the provision of health ...
Industrial Production and Quality Control of Snake Antivenoms
(2014)
The production of snake antivenoms involves stages such as production of venom, immunization of animals to generate hyperimmune plasma, immunoglobulin purification, viral inactivation (or removal), and stabilization of the ...
12-HETE is a regulator of PGE2 production via COX-2 expression induced by a snake venom group IIA phospholipase A2 in isolated peritoneal macrophages
(2020)
The snake venom myotoxin (MT)-III is a group IIA secreted phospholipase A2 (sPLA2) with pro-inflammatory activities. Previous studies have demonstrated that MT-III has the ability to stimulate macrophages to release ...