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Insulin resistance and impaired glucose tolerance in overweight and obese Costa Rican schoolchildren
(2008)
Background. Worldwide obesity has become an unprecedented public health challenge. In addition, a notable increase in the risk of insulin resistance and type 2 diabetes mellitus has emerged. In Costa Rica, there are no ...
Virulent Brucella nosferati infecting Desmodus rotundus has emerging potential due to the broad foraging range of its bat host for humans and wild and domestic animals
(2023)
Desmodus rotundus, vampire bats, transmit dangerous infections, and brucellosis is a hazardous zoonotic disease, two adversities that coexist in the subtropical and tropical areas of the American continent. Here, we report ...
Partial efficacy of a Brazilian coralsnake antivenom and Varespladib to neutralize distinct toxic effects induced by a sublethal Micrurus dumerilii carinicauda envenoming in rats
(2022)
In this work, we reported the efficacy of a combination of Brazilian therapeutic coralsnake antivenom (CAV) and varespladib (phospholipase A2 inhibitor – VPL) in partially neutralizing selected toxic effects of Micrurus ...
Effect of Bothrops asper (Fer-De-Lance) snake venom on erythrocyte membrane. A comparative study
(1992-02)
1. The effect of Bothrops asper venom on erythrocytes of different species, sheep erythrocyte ghost vesicles and liposomes made of phospholipids from sheep erythrocytes was studied. 2. B. asper venom had a direct hemolytic ...
Development of immunoassays for determination of circulating venom antigens during envenomations by coral snakes (Micrurus species)
(1997-11)
A reverse agglutination assay and two capture enzyme-linked immunoassays (ELISAs) for the quantitative determination of Micrurus nigrocinctus nigrocinctus venom antigens in fluids were developed using affinity-purified ...
The STR polymorphism (AAAAT)n within the intron 1 of the tumor protein 53 (TP53) locus in 17 populations of different ethnic groups of Africa, America, Asia and Europe
(Revista de Biología Tropical, 52(3):645-657, 2004)
The SIR (A.AAAT). within intron 1 of the TP53 Locus was screened in 17 populations from 3 main
ethnic groups: Europeans, Asiatics, and Africans. and from the hybrid population of Costa Rica (1968 samples).
Three alleles, ...
Susceptibilidad de Trypanosoma cruzi a diferentes venenos de serpientes de Costa Rica
Susceptibility of Trypanosoma cruzi to different Costa Rican snake venoms
(2008)
Se evaluaron los efectos tóxicos de los venenos de cinco serpientes costarricenses en
cuanto a su capacidad tripanocida contra dos cepas de Trypanosoma cruzi y sus efectos en cuanto
a los mecanismos de muerte celular. ...
A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms
(Biochimica et Biophysica Acta - Proteins and Proteomics 1844(12):2265-2276, 2014-12)
Envenomation via snakebites is an important public health problem in many tropical and subtropical countries that, in addition to mortality, can result in permanent sequelae as a consequence of local tissue damage, which ...
Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping
(2017-07)
Snakebite antivenom is a 120 years old invention based on polyclonal mixtures of antibodies
purified from the blood of hyper-immunized animals. Knowledge on antibody recognition
sites (epitopes) on snake venom proteins ...
Surprising SES Gradients in Mortality, Health, and Biomarkers in a Latin American Population of Adults
(Journal of Gerontology: Social Sciences 64B(1):105-117, 2009-02-04)
Background. To determine socioeconomic status (SES) gradients in the different dimensions of health among elderly
Costa Ricans. Hypothesis: SES disparities in adult health are minimal in Costa Rican society.
Methods. ...