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A potent antihemorrhagin in the serum of the non-poisonous water snake Natrix tessellata: isolation, characterization and mechanism of neutralization
(1994-12)
The main natural antihemorrhagic factor (NtAH), which inhibits the hemorrhagic activity of Bothrops asper snake venom, was isolated from the serum of the non-poisonous water snake Natrix tessellata by ammonium sulfate ...
The synthetic Varespladib molecule is a multi-functional inhibitor for PLA2 and PLA2-like ophidic toxins
(2021)
The treatment for snakebites is early administration of antivenom, which can be highly effective in inhibiting the systemic effects of snake venoms, but is less effective in the treatment of extra-circulatory and local ...
Culicidofauna asociada con contenedores artificiales en la comunidad “La Carpio”, Costa Rica
(2009-06-01)
Objetivo:
Determinar las especies de mosquitos más frecuentes
en “La Carpio”, primer comunidad del Área Metropolitana de
San José en sufrir un brote por dengue.
Métodos:
Cuatro encuestas larvales fueron ...
Comparison of the effect of Crotalus simus and Crotalus durissus ruruima venoms on the equine antibody response towards Bothrops asper venom: Implications for the production of polyspecific snake antivenoms
(2011-02)
Antivenoms are preparations of immunoglobulins purified from the plasma of animals immunized with snake venoms. Depending on the number of venoms used during the immunization, antivenoms can be monospecific (if venom from ...
La participación comunitaria como recurso para la prevención del dengue en una comunidad urbana de San José, Costa Rica
(2005-06-01)
Se implementó un modelo de participación comunitaria en dos de los cuatro sectores del caserío "La Carpio ",Distrito Uruca,San José, Costa Rica,el cual constituyó el primer poblado del Gran Área Metropolitana de San José ...
Phospholipase A2 and inflammation
Pathobiological activities of human group II phospholipase A2 in inflammation: do they all depend on its enzymatic action?
(1995)
Increased expression of secreted group II phospholipase A 2 (sPLA2) is associated with inflammation 1.This enzyme can promote a variety of potentially harmful events, which have been attributed to its catalytic activity. ...
Isolation of a Toxigenic and Clinical Genotype of Clostridium difficile in Retail Meats in Costa Rica
(2013-02)
We isolated a regional toxigenic genotype of Clostridium difficile, previously found in human infection in 4 of 200 (2%) samples of retail meats for human consumption: 1 of 67 samples of beef, 2 of 66 of pork, and 1 of 67 ...
In vivo neutralization of the dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG monoclonal antibodies
(2018)
The black mamba (Dendroaspis polylepis) is one of the most feared snake species of the
African savanna. It has a potent, fast-acting neurotoxic venom comprised of dendrotoxins and
α-neurotoxins associated with high ...
In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors
(2022)
Despite vaccines are the main strategy to control the ongoing global COVID-19
pandemic, their effectiveness could not be enough for individuals with
immunosuppression. In these cases, as well as in patients with ...