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A Second Locus for an Axonal Form of Autosomal Recessive Charcot-Marie-Tooth Disease Maps to Chromosome 19q13.3
(American Journal Human Genetic ; 68 (1 p. 269-274, 2001)
Autosomal recessive Charcot-Marie-Tooth disease (CMT) represents a heterogeneous group of disorders affecting the peripheral nervous system. The axonal form of the disease is designated as "CMT type 2" (CMT2), and one locus ...
Mitochondrial polymorphisms are associated both with increased and decreased longevity
(Hum Hered 2009;67:147–153, 2008-12-15)
Previous work compared frequency of longevity-associated polymorphisms (LAPS) in long-lived individuals and in controls from the general population (primarily in Europe and Japan), suggesting the polymorphisms are responsible ...
Direct screening of a mitochindrial DNA deletion valuable for Ameridian evolutionary research [resumen]
(1994)
A rapid, simple restriction isotyping method is described for the direct screening of a previously characterized Amerindian mitochondrial DNA (mtDNA) marker ;onsisting of a 6-bp "Huetar" deletion. In a sample of 31 maternally ...
Las malformaciones congénitas en Costa Rica. II (Estudio retrospectivo hospitalario de caso-control)
(1985)
Se realizó un estudio retrospectivo de caso-control de malformaciones congénitas en Costa Rica, utilizando expedientes clínicos de los Hospitales Nacional de Niños Carlos Sáenz Herrera y la Maternidad Carit, entre 1970 y ...
Genetic variation at twentythree microsatellite loci in sixteen human populations
(1999-08)
We have analysed genetic variation at 23 microsatellite loci in a global sample of 16 ethnically and geographically diverse human populations. On the basis of their ancestral heritage and geographic locations, the studied ...
Genetic variation and racial admixture in the Miskito of the southern Mosquito Shore, Nicaragua
(1998)
A survey of the electrophoretic variation at eleven loci red-blood cell enzymes. hemoglobins and serum proteins was performed on a sample of 59 Miskitos stemming from the southernmost part of the Mosquito shore of Nicaragua. ...
Mitochondrial DNA “clock” for the Amerinds and its implications for timing their entry into North America
(1994-02)
Students of the time of entry of the ancestors of the Amerinds into the New World are divided into two camps, one favoring an "early" entry [more than approximately 30,000 years before the present (YBP)], the other favoring ...
Microevolution in lower Central America: Genetic characterization of the Chibcha-speaking groups of Costa Rica and Panama, and a consensus taxonomy based on genetic and linguistic affinity
(1990)
There is evidence that Amerindians have continuously occupied the lower Central American Isthmus for as
long as 10,000 years. There remains some doubt about the relationships of these original colonizers to the
resident ...
High mitochondrial mutation rates estimated from deep-rooting Costa Rican pedigrees
(American Journal of Physical Anthropology 2012 July ; 148(3): 327–333., 2012-07)
Estimates of mutation rates for the noncoding hypervariable Region I (HVR-I) of mitochondrial
DNA (mtDNA) vary widely, depending on whether they are inferred from phylogenies (assuming
that molecular evolution is clock-like) ...
Migration and Genetic Infrastructure of the Central American Guaymi and Their Affinities With Other Tribal Groups
(American Journal of Phisical Antropology: 58 p.201-214, 1982-06)
New genetic data on 40 red cell enzymes, antigenic blood groups, and serum proteins representing 42 separate loci, are reported for two Guaymi communities in Southeastern Costa Rica. These two settlements, Limoncito and ...