• Antiagregantes plaquetarios: ¿En dónde se encuentran las diferencias? 

      Chaverri Fernández, José Miguel; Díaz Madriz, José Pablo; Cordero García, Eugenia; Ramírez Medina, José Pablo; Villalta, Karina; Zavaleta Monestel, Esteban (2017)
      Las guías de tratamiento apoyan el uso de antiagregantes plaquetarios como parte de la prevención y manejo de la enfermedad arterial coronaria, debido a la existencia de evidencia clínica que respalda el beneficio en la ...
    • Aplicaciones terapéuticas del eculizumab 

      Campos González, Natalia; Ruiz Jiménez, Susana; Rodríguez Jiménez, Johanna; Chacón Jiménez, Luz María (2022-05)
      Introducción: El eculizumab es un anticuerpo monoclonal de tipo IgG diseñado para el tratamiento de la hemoglobinuria paroxística nocturna (HPN), en el que su diana farmacológica forma parte del sistema del complemento. ...
    • Characterization and Comparison of quality management systems for cosmetic products in the world 

      Madrigal Redondo, German Leonardo; Rojas Salas, María Fernanda; Chavarría Rojas, Marianela; González Corrales, Daniela; Pérez Navarro, Esteban; Robles Barquero, Mariangel (2021)
      The quality management systems are tools that can be implemented in different types of industry with the purpose of achieving improved quality standards on the products or services they develop, mainly looking to satisfy ...
    • Ethnobotany, Chemical Constitution and Biological Activities of Moquilea Genus: A Systematic Review 

      Delgado Rodríguez, Fabián Vinicio; Porras Navarro, Marta; Villalobos Gätjens, Natalia; Sandí Flores, Jeniffer; Chaves Hernández, Valeria (2022-01)
      Moquilea (Chrysobalanaceae) is a taxon recently separated from previous Licania genus. Several plants from Moquilea genus have been studied for the evaluation of their biological properties and chemical constitution analysis, ...
    • Ethnobotany, Pharmacology and Major Bioactive Metabolites from Impatiens Genus Plants and their Related Applications 

      Delgado Rodríguez, Fabián Vinicio; Weng Huang, Nien Tzu; Loría Gutiérrez, Arlene; Arias Núñez, David; Rosales Leiva, Christopher (2023-11-27)
      Impatiens genus comprises several species important for agriculture and food industries, ethnobotany, and research in pharmacology, phytochemistry, biotechnology and pharmaceutical sciences. In this paper, a systematic ...
    • Gelatin and non gelatin soft gel capsules: A review 

      Chavarría Rojas, Marianela; Acuña Amador, Daniel; Madrigal Redondo, German (2021-06-26)
      Soft gelatin capsules are solid, single-dose dosage forms consisting of a shell, usually made from gelatin, that generally contain liquids. Gelatin is the most widely used film-forming agent, and it is extracted from ...
    • General aspects about Allium sativum - a review 

      Loría Gutiérrez, Arlene; Blanco Barrantes, Jeimy; Porras Navarro, Marta; Ortega Monge, María Celeste; Cerdas Vargas, María José; Madrigal Redondo, German (2021-09-20)
      Introduction: Garlic has been used as a food and medicinal plant through the years. Antimicrobial, antiviral, and immunostimulatory effects are attributed to garlic, so it is widely recommended to treat diseases like asthma, ...
    • Ginsenosides and other Phytochemicals of Panax spp. Properties and uses in the pharmaceutical field 

      Solís Vindas, Gretel; Chavarría Rojas, Marianela; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Madrigal Redondo, German (2021)
      Introduction: Ginseng has been used since ancient times, for its medicinal properties. This plant comes from the genus Panax, and the most representative species are Panax quinquefolium, Panax ginseng, and Panax ...
    • Modulación Alostérica Positiva selectiva para el receptor muscarínico M1: descubrimiento y desarrollo del compuesto VU0486846 y su importancia para el desarrollo terapéutico tratamientos para el Alzheimer y la esquizofrenia 

      Vargas Monge, Ronny; Soley, Jordi (2021-12-20)
      Objetivo: Ejecutar una revisión sistemática sobre las estrategias de desarrollo terapéutico para Alzheimer y es-quizofrenia basadas en la modulación alostérica positiva del receptor M1.Método: Se realizó una ...
    • Organ-on-a-Chip systems for new drugs development 

      Vargas Monge, Ronny; Medina, Laura; Egurbide Sifre, Andrea (2021-03-22)
      Research on alternatives to the use of animal models and cell cultures has led to the creation of organ-ona-chip systems, in which organs and their physiological reactions to the presence of external stimuli are simulated. ...
    • Radiopharmaceuticals: a mini review of applications and innovations on nuclear medicine 

      Mora Román, Juan José; Esquivel Álvarez, Alejandro; Quesada Morales, Elías; Villegas Calero, María Paz; Chavarría Rojas, Marianela; Rojas Salas, María Fernanda; Madrigal Redondo, German (2021-10)
      Radiopharmaceuticals are a group of medicines known for their radioactive agents, known as radioisotopes. They are employed in various areas, primarily clinics for the diseases' diagnosis or treatment. Their structure ...