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Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate
(2018)
It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ...
Physicochemical characterization of therapeutic peloids from the surroundings of Costa Rica Arenal Volcano
(2015)
Costa Rica is a volcanic country, containing a variety of peloids with different physicochemical properties; also its main
source of income is the tourism. Most of their abundant natural resources have not been characterized ...
Determination of the Impact Caused by Direct Compression on the Crystalline State of Rupatadine Fumarate 10 mg Tablets
(2019-11-08)
The aim of this study is to determine the impact caused by direct compression on the crystalline state of two
prototypes of Rupatadine fumarate 10 mg tablets. The tablets were manufactured through direct compression. ...
Design of Experiments for the Establishment of the Dissolution Test Conditions of Rupatadine Fumarate 10 mg tablets
(2019)
Design of Experiments (DoE) is a statistical model that aims to determine if the factors under study affect the response, and if so, it determines
the conditions under which this variable of interest can be optimized. In ...
Physicochemical Characterization of a Liposomal Formulation Based on Glucosamine and Vitamin D, Commercialized as a Nutritional Supplement
(2018)
In the last years, the transport and release mechanism of bioactive compounds has been studied.
The liposomes are multivesicular systems that enhance the absorption, stability, and transport of
these compounds. The ...
Quality control performed on liposomal formulations based on guarana extract, vitamins a, c, e, b1, b2, b5, b6, b12, biotin and folic acid, used as nutritional products
(2017)
The study of has increased in the last decades. One of the mechanisms that has acquired great relevance is to formulate using liposomal vesicles. Liposomes are structures that enh and transport of active compounds, which ...
Identification of rupatadine fumarate polymorphic crystalline forms in pharmaceutical raw materials
(2018)
Polymorphism analysis of pharmaceutical raw materials is considered one of the most relevant
evaluations that should be done. As we know, different crystal forms from the same molecule have
differences in terms of their ...
Multi-vesicular phosphatidylcholine liposomes as vehicles for curcumin in a nutritious drinkable formulation
(2017)
Liposomal vesicles are used as a strategy to enhance the stability and bioavailability of its bioactive components.
Large part of its characteristics can be attributed to the likeness between the liposomal and biological ...
Rubus adenotrichus fruit extracts phytochemical characterization and antioxidant power evaluation for dermocosmetic formulations
(2017)
There are more than 700 species of the genus Rubus, popularly known as Mora (tropical
highland blackberry). In Costa Rica, the species Rubus adenotrichus has been characterized
by its high content of antioxidant substances, ...
Phytochemical characterization of extracts of the mesocarp of Bactris gasipaes and evaluation of its antioxidant power for pharmaceutical dermal formulations
(2019)
The Bactris gasipaes is a native palm from Central America which its fruit is known as pejibaye, its
wood is also used for the manufacture of various utensils, the marrow of its tender stems is edible and it
is called ...