Now showing items 1-2 of 2

    • Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis 

      Sidhu, Alpa; Miller, Justin R.; Tripathi, Ashootosh; Garshott, Danielle M.; Brownell, Amy L.; Chiego, Daniel J.; Arevang, Carl Johan; Zeng, Qinghua; Jackson, Leah C.; Bechler, Shelby A.; Callaghan, Michael U.; Yoo, George H.; Sethi, Seema; Lin, Ho-Sheng; Callaghan, Joseph H.; Tamayo Castillo, Giselle; Sherman, David H.; Kaufman, Randal J.; Fribley, Andrew M. (2015)
      Oral squamous cell carcinoma (OSCC) is the most common cancer affecting the oral cavity, and US clinics will register about 30,000 new patients in 2015. Current treatment modalities include chemotherapy, surgery, and ...
    • Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts 

      Cruz, Patricia G.; Fribley, Andrew M.; Miller, Justin R.; Larsen, Martha J.; Schultz, Pamela J.; Jacob, Renju T.; Tamayo Castillo, Giselle; Kaufman, Randal J.; Sherman, David H. (2015-07-06)
      As part of the International Cooperative Biodiversity Groups (ICBG) Program, we were interested in identifying biologically active unfolded protein response (UPR) inducing compounds from marine microorganisms isolated from ...