Browsing Química by Title
Now showing items 167-186 of 321
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Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor
(2013)Topoisomerase inhibitors are effective for antibacterial and anticancer therapy because they can lead to the accumulation of the intermediate DNA cleavage complex formed by the topoisomerase enzymes, which trigger cell ... -
Identification of polyphenols from antiviral Chamaecrista nictitans extract using high-resolution LC–ESI–MS/MS
(2014)Chamaecrista nictitans (L) extract possesses antiviral properties; it acts against the herpes simplex virus, and this may be attributed to its constituent phenolics. Here, high-resolution LC–ESI–MS/MS is used to identify ... -
Identification of Protein Kinase C Activation as a Novel Mechanism for RGS2 Protein Upregulation through Phenotypic Screening of Natural Product Extracts
(2014)Biochemical high-throughput screening is widely used in drug discovery, using a variety of small molecule libraries. However, broader screening strategies may be more beneficial to identify novel biologic mechanisms. In ... -
Implementación de un sistema de evaluación de riesgo en una industria farmacéutica aplicando la herramienta fmea (failure mode effect and analysis) como instrumento para determinar los atributos de calidad en la evaluación de procesos
(2021-09-09)En el 2019, se desarrolla la implementación de una metodología de evaluación de riesgos aplicada a procesos farmacéuticos, con la finalidad de detectar fallas y puntos de mejora. Inicialmente, se realiza un entrenamiento ... -
Influence of bitumen and aggregate polarity on interfacial adhesion
(2017)The quality of the bitumen–aggregate interface formed in an asphalt mixture is dictated by the physicochemical properties of both materials, such as surface polarity. In order to better understand the role of polarity on ... -
Influence of nanosilica and diatomite on the physicochemical and mechanical properties of binder at unaged and oxidized conditions
(2016)Modification of binders helps address common distresses in pavements by changing their essential properties. In order to further characterize the role of additives in these changes, a set of nanosilica and diatomite modified ... -
Influence of rice field agrochemicals on the ecological status of a tropical stream
(2016-01-15)Many tropical countries contain a high density of protected ecosystems, and these may often be bordered by intensive agricultural systems. We investigated the chemical and ecological status of a stream connecting an area ... -
Inhibition of granulocyte elastase activity by caffeic acid derivatives
(1999)In former studies it was shown that bornyl derivates may contribute to the anti-inflamatory activity of some drugs, such as Verbesia turbacensis, Notopterygium incisum or Coreopsis mutica. -
Isolation of Major Components from the Roots of Godmania aesculifolia and Determination of Their Antifungal Activities
(2013)From the methanol root extract of Godmania aesculifolia, a species selected in a multinational OAS program aimed at discovering antifungal compounds from Latin American plants, a new chavicol diglycoside (1), the known ... -
Kaurene diterpenes from Mikania vitifolia
(1998)From the aerial parts of Mikania vitifolia three new ent-kaurane diterpenes, ent-7α-cinnamoyloxy-15β-hydroxy-kaur-16-en-19-oic acid, ent-15β-cinnamoyloxy-7α-hydroxy-kaur-16-en-19-oic acid and ent-15β-hydroxy-7α-(E)-lachn ... -
Kinetik und Thermodynamik einer thermischen Umlagerung in der λ5-Phosphorinreihe. Die Umlagerung von 1-Acetoxy-λ5-phosphorin* in 6-Acetyl-1-oxo-1λ5-phospha-2,,4-cyclohexadien
(1974-03)Beim Erhitzen von 1-Acetoxy-1-isopropoxy-2,4,6-triphenyl-λ5-phosphorin (1c) in 1,4-Dioxan entsteht 6c-Acetyl-1-isopropoxy-1r-oxo-2,4,6-triphenyl-1λ5-phospha-2,4-cyclohexadien (2c), das durch säurekatalysierte Epimerisierung ... -
Light Reflection by Cuticles of Chrysina Jewel Scarabs: Optical Measurements, Morphology Characterization, and Theoretical Modeling
(2016)Cuticles of some Chrysina scarabs are characterized by flat, graded, and twisted structures of nanosized chitin fibrils. As inferred from SEM images, each species has its own spatial period or pitch P which is dependent ... -
Low CyaA expression and anti‐cooperative binding of cAMP to CRP frames the scope of the cognate regulon of Pseudomonas putida
(2021-03)Although the soil bacterium Pseudomonas putida KT2440 bears a bona fide adenylate cyclase gene (cyaA), intracellular concentrations of 30,50-cyclic adenosine monophosphate (cAMP) are barely detectable. By using reporter ... -
Manganese and cobalt redox cycling in laterites; Biogeochemical and bioprocessing implications
(2020)Cobalt is essential for the modern technology that underpins the decarbonisation of our economies, but its supply is limited leading to its designation as a critical metal. Cobalt biogeochemistry is poorly understood, yet ... -
Medicinal plants popularly used for gastrointestinal disorders in Costa Rican Central Valley
(2004)Abstract : A survey was conducted of medicinal plants for gastrointestinal disorders used by inhabitants of the Central Valley in Costa Rica by means of interviews with medicinal plant vendors of the central markets of the ... -
Metales traza (As, Cd, Co, Cr, Ni, Pb) en plantaciones bananeras de Costa Rica y efecto del cromo en el crecimiento y la absorción de nutrimentos en plantas de banano (Musa AAA)
(2021)Los metales traza son elementos que se encuentran en bajas concentraciones en el ambiente, generalmente menores a mil partes por millón. Algunos de estos elementos son requeridos en el ciclo de vida ... -
Metals in coastal mollusks of Costa Rica
(2015-12)The input of contaminants to coastal ecosystems is a global problem on the rise. Data on metal pollution from tropical sites is often lacking and pilot surveys are urgently needed to provide a general framework to estimate ... -
Methylotrophs and Hydrocarbon-Degrading Bacteria Are Key Players in the Microbial Community of an Abandoned Century-Old Oil Exploration Well
(2021-04-17)In this work, we studied the microbial community and the physicochemical conditions prevailing in an exploratory oil well, abandoned a century ago, located in the Cahuita National Park (Costa Rica). According to our analysis, ...