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Differential volatile organic compound expression in the interaction of Daldinia eschscholtzii and Mycena citricolor
(2023)
Fungi exhibit a wide range of ecological guilds, but those that live within the inner
tissues of plants (a.k.a. endophytes) are particularly relevant due to the benefits they
sometimes provide to their hosts, such as ...
Screening of Latin American Plants for Cytotoxic Activity
(2006)
The SRB cytotoxicity assay was used to screen plant extracts, in a collaborative multinational OAS project involving Argentina, Bolivia, Colombia, Costa Rica, Guatemala, Nicaragua and Panama, against breast (MCF-7), lung ...
Naphthalenones and Isocoumarins from a Costa Rican Fungus Xylariaceae sp. CR1546C
(2014)
A new naphthalenone, (R)-4,6,8-trihydroxy-3,4-dihydro-1(2H)-naphthalenone and a new isocoumarin, 6,8-dihydroxy-(3R)-(2-oxopropyl)-3,4-dihydroisocoumarin, together with eight related known compounds were isolated from the ...
β-Carboline monoterpenoid glucosides from Palicourea adusta
(1999)
Lyaloside, a monoterpenoid glucoindole alkaloid, was isolated from the leaves of Palicourea adusta together with a mixture of its hydroxycinnamic acid derivatives, (E)-O-(6′)-cinnamoyl-4″-hydroxy-3″-methoxy-lyaloside and ...
Diterpenes and sesquitrpenes from Mikania banisteriae
(1997)
Two new ent-kaurane diterpenes, 18,19-diacetoxy-ent-kaur-16-ene and 17-oxo-ent-kaur-15(16)-en-18-oic acid, were isolated from the aerial parts of Mikania banisteriae, together with the known ent-kauranes ent-kaur-16-en-18-oic ...
Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor
(2013)
Topoisomerase inhibitors are effective for antibacterial and anticancer therapy because they can lead to the accumulation of the intermediate DNA cleavage complex formed by the topoisomerase enzymes, which trigger cell ...
The Combined Use of Alphavirus Replicons and Pseudoinfectious Particles for the Discovery of Antivirals Derived from Natural Products
(2015)
Alphaviruses are a prominent class of reemergent pathogens due to their globally expanding ranges, potential for lethality, and possible use as bioweapons. The absence of effective treatments for alphaviruses highlights ...
Ent-clerodane derivatives and other constituents from representatives of the subgenus ageratina
(1989)
Ageratina ixiocladon afforded several p-hydroxyacetophenone derivatives and diterpenes including six new ent-clerodanes. Two further species, which are also placed in the subgenus Ageratina, gave p-hydroxyacetophenone ...
Empleo de técnicas y materiales biológicos en la búsqueda de productos activos contra la malaria
(2001)
Se describen los métodos empleados en el estudio del efecto de extractos de insectos preparados en el Instituto Nacional de Biodiversidad de Costa Rica, sobre un tipo de malaria murina producida por el Plasmodium bergheim. ...
Bioactivity of prenylated hydroxybenzoic acids from Piper garagaranum C. DC
(2022)
A bio-assay guided fractionation of Piper garagaranum C. DC. led to the isolation of two prenylated hydroxybenzoic
acids (1-2) with anti-inflammatory and cytotoxic activities. The anti-inflammatory action was determined
in ...