Phytochemical study of endemic Costa Rican Annonaceae species Annona pittieri and Cymbopetalum costaricense
artículo original
Fecha
2021Autor
Parra Villalobos, Jonathan
De Ford, Christian
Murillo Masís, Renato
Metadatos
Mostrar el registro completo del ítemResumen
Phytochemical profile of the Central American rainforest endemic Annonaceae species, Annona pittieri and Cymbonopetallum costaricense, were studied in search
of novel bioactive compounds. The acetogenin squamocin (1) isolated from A. pittieri showed cytotoxic activity against human acute lymphocytic leukaemia with
low activity against healthy blood cells. In addition, other eight compounds were isolated from A. pittieri, including a novel 2-azaanthraquinone alkaloid,
4-methoxybenzo[g]isoquinoline-5,10-dione (2). Furthermore, from C. costaricense three compounds were isolated including a novel 1-azaanthraquinone alkaloid,
6-hydroxy-9-methoxy-cleistopholine (3)
External link to the item
10.4067/S0717-97072021000105047Colecciones
- Química [360]