Diagnosis of Schizophrenia in Latino Populations. A Comparison of Direct Interview and Consensus Based Multi-Source Methods
artículo original
Date
2009-07Author
Dassori, Albana
Medina, Rolando
Ontiveros Sánchez de la Barquera, Jose Alfonso
Nicolini Sánchez, José Humberto
Muñoz, Rodrigo
Escamilla, Michael
Contreras Rojas, Javier
Raventós Vorst, Henriette
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Show full item recordAbstract
We determined the rates of agreement between diagnoses, using
the Diagnostic Interview for Genetic Studies (DIGS) and diagnoses arrived
at, using additional sources of information, to establish whether there are
differences in agreement between direct interview diagnoses at US and
non-US sites in comparison best estimate consensus process and to identify
diagnoses that could increase diagnostic error when only the DIGS is used.
DIGS diagnoses were compared with consensus diagnoses that used the same
DIGS interview, plus Family Interview for Genetic Studies (FIGS) and
review of medical records in 342 psychotic subjects. We found similar
numbers of subjects diagnosed with schizophrenia (225 by direct interview,
and 232 by consensus process). The majority of those “misdiagnosed” by
direct interview had mood disorder by the consensus. Over 10% of the total
subjects diagnosed by direct interview as not meeting criteria for schizophrenia
had schizophrenia by consensus. There were no statistically significant
differences between countries (US vs. non-US sites) in the agreement
rate between direct interview diagnosis and consensus diagnosis. In conclusion,
a final best-estimate process is essential to make diagnostic distinctions
and to reduce diagnostic misclassifications for both research studies and in
clinical practice
External link to the item
10.1097/NMD.0b013e3181aac935
artículo (arbitrado)--Universidad de Costa Rica, Centro de Investigación en Biología Celular y Molecular. 2009. Este documento es privado debido a limitaciones de derechos de autor.