Microbiología
Envíos recientes
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A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption
(2016-08)The epidemiology of Clostridium difficile infections is highly dynamic as new strains continue to emerge worldwide. Here we present a detailed analysis of a new C. difficile strain (ICC-45) recovered from a cancer patient ... -
A biocomputational platform for the automated construction of large-scale mathematical models of miRNA-transcription factor networks for studies on gene dosage compensation
(2016-11-09)Cancer complexity and resistance is mediated by cell-to-cell heterogeneity, which is the consequence of the enormous instability of its genetic material. It is unknown how cancer cells are able to withstand the effects ... -
Arboviral encephalitis in Costa Rican horses: 2009-2016
(2016-12)Arbovirus of the genus Alphavirus and Flavivirus can cause febrile illness and sometimes neurological disease in both humans and animals. West Nile Virus (WNV), Eastern Equine Encephalitis Virus (EEEV), Western Equine ... -
Highly individual patterns of virus‑immune IgG effector responses in humans
(2016-05-18)t IgG responses are fundamental to adaptive immunity and document immunological memory of previous pathogen encounter. While specific antigen recognition is mediated by the variable F(ab′)2 domain of IgG, various effector ... -
Molecular Characterization of Two Major Dengue Outbreaks in Costa Rica
(2016-07)Dengue virus (DENV) (Flavivirus, Flaviviridae) is a reemerging arthropod-borne virus with a worldwide circulation, transmitted mainly by Aedes aegypti and Aedes albopictus mosquitoes. Since the first detection of its ... -
Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom
(2016-09-15)A chicken-derived antivenom (ChDAv) towards taipan snake (Oxyuranus scutellatus) venom was produced by purifying anti-taipan IgY from egg yolks of hens immunized with taipan venom. The productivity, antivenomic profile, ... -
The need for an integrated approach in confronting snakebite envenoming in Latin America: the relevance of endogenous scientific and technological research
(2016)Snakebite envenomings constitute a serious public health problem on a global level, especially in Africa, Asia and Latin America. In our Latin American region, it is estimated that at least 70,000 snakebite cases occur ... -
El virus del Zika
(2016-01)El virus del Zika es un arbovirus emergente. Se transmite por medio de los mosquitos del género Aedes. Fue descrito por primera vez en mosquitos y monos del bosque Zika en Uganda, en 1947; posteriormente, en seres humanos ... -
Molecular detection of Clostridium difficile on inert surfaces from a Costa Rican hospital during and after an outbreak
(2016-12-01)Background: Hospital transmission of Clostridium difficile is fostered by contamination of surfaces and medical equipment with spores highly resistant to disinfectants and regular cleaning procedures. Despite the outbreaks ... -
Evaluación de la resistencia a insecticidas en cepas de Aedes aegypti (Diptera Culicidae) de la Región Caribe de Costa Rica
(2016-01)Introducción: el dengue y chikungunya son virosis antroponóticas transmitidas por Aedes aegypti que afectan extensas áreas del continente americano incluyendo Costa Rica. La reciente introducción del virus Zika representa ... -
Exposure of dogs to spotted fever group rickettsiae in urban sites associated with human rickettsioses in Costa Rica
(2016-07)The zoonotic transmission cycles of Rickettsia rickettsii and other spotted fever group (SFG) rickettsiae in Latin America have usually been associated with rural or sylvatic environments, although domestic dogs can be ... -
Detection of rickettsiae in fleas and ticks from areas of Costa Rica with history of spotted fever group rickettsioses
(2016-10)Outbreaks of spotted fevers have been reported in Costa Rica since the 1950s, although vectors responsible for transmission to humans have not been directly identified. In this study, species of Rickettsia were detected ... -
Prevalencia de Fasciola hepatica y pérdidas económicas asociadas al decomiso de hígados en tres mataderos de clase A de Costa Rica
(2016)Para estimar la prevalencia anual y mensual de Fasciola hepatica y las pérdidas económicas anuales asociadas al decomiso de hígados por presencia del parásito, se analizaron los registros del Ministerio de Agricultura ... -
Prevalencia de fasciolosis en bovinos de Costa Rica (2014). Comparación de cuatro técnicas diagnósticas
(2016)Se realizó un estudio transversal con el objetivo de determinar la prevalencia de fasciolosis en bovinos sacrificados en mataderos de Costa Rica y comparar cuatro técnicas diagnósticas disponibles (inspección macroscópica ... -
Biopiracy of natural products and good bioprospecting practice
(2016-02-15)Background: Biopiracy mainly focuses on the use of biological resources and/or knowledge of indigenous tribes or communities without allowing them to share the revenues generated out of economic exploitation or other ... -
Identification of cancer chemosensitivity by ODE and GMM modeling of heterogeneous cellular response to perturbations in fluorescent sphingolipid metabolism
(2016-11-11)Cancer refers to a group of diseases in which cells display uncontrolled growth. Chemotherapy options are usually conditioned by generating resistance which is explained in part by the intrinsic heterogeneity of the ... -
N-Formyl-Perosamine Surface Homopolysaccharides Hinder the Recognition of Brucella abortus by Mouse Neutrophils
(2016-06)Brucella abortus is an intracellular pathogen of monocytes, macrophages, dendritic cells, and placental trophoblasts. This bacterium causes a chronic disease in bovines and in humans. In these hosts, the bacterium also ... -
Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains
(2016-09-29)Brucellosis is a bacterial infectious disease affecting a wide range of mammals and a neglected zoonosis caused by species of the genetically homogenous genus Brucella. As in most studies on bacterial diseases, research ... -
Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities
(2016-03)Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased pathogenic potential of these strains has been attributed to several factors but is still ... -
Zika Virus (ZIKV): A New Emerging Pathogen Transmitted by Aedes Mosquitoes (Diptera: Culicidae) in the Latin American Subcontinent
(2016-03-11)Aedes aegypti and Aedes albopictus (Diptera: Culicidae) are two species of synanthropic mosquitoes that are common in outdoor and indoor domiciliary environments in tropical countries. Their vectorial competence and ...
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