Envíos recientes

  • CMV-encoded Fcγ receptors: modulators at the interface of innate and adaptive immunity 

    Corrales Aguilar, Eugenia; Hoffmann, Katja; Hengel, Hartmut (2014-10-07)
    The constant region of IgG antibodies mediates antiviral activities upon engaging host Fcγ receptors (FcγRs) expressed by a variety of immune cells, such as antibody-dependent cellullar cytotoxcity (ADCC) executed by natural ...
  • Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and III 

    Corrales Aguilar, Eugenia; Trilling, Mirko; Hunold, Katja; Fiedler, Manuela; Le, Vu Thuy Khanh; Reinhard, Henrike; Ehrhardt, Katrin; Mercé Maldonado, Eva; Aliyev, Enver; Zimmermann, Albert; Johnson, David C.; Hengel, Hartmut (2014-05-15)
    Human cytomegalovirus (HCMV) establishes lifelong infection with recurrent episodes of virus production and shedding despite the presence of adaptive immunological memory responses including HCMV immune immunoglobulin G ...
  • Neotropical Bats from Costa Rica harbour Diverse Coronaviruses 

    Moreira Soto, Andrés; Taylor Castillo, Mayra Lizeth; Vargas Vargas, Nancy; Rodríguez Herrera, Bernal; Jiménez Centeno, Carlos; Corrales Aguilar, Eugenia (2015-02-04)
    Bats are hosts of diverse coronaviruses (CoVs) known to potentially cross the host–species barrier. For analysing coronavirus diversity in a bat species-rich country, a total of 421 anal swabs/faecal samples from Costa ...
  • Neotropical primary bat cell lines show restricted dengue virus replication 

    Moreira Soto, Andrés; Soto Garita, Claudio; Corrales Aguilar, Eugenia (2017-02)
    Dengue is the most widespread arboviral disease affecting humans. Bats are recognized carriers of emerging viral zoonoses and have been proposed as dengue reservoirs, since RNA/NS1 and/or antiviral antibodies have been ...
  • Mapping the risk of Aedes aegypti larval habitats using tree cover in Puntarenas, Costa Rica 

    Troyo Rodríguez, Adriana; Calderón Arguedas, Ólger; Avendaño López, Adrián; Mora Pineda, Geovanny; Fuller, Douglas O. (2010-08)
    Tree cover and other characteristics of urban structure have been associated in urban environments with abundance and productivity of Aedes aegypti and other mosquito larval habitats. Tree cover can conceal containers, ...
  • Modeling dengue cases in health Regions of Costa Rica using El Niño Southern Oscillation and local vegetation dynamics 

    Troyo Rodríguez, Adriana; Fuller, Douglas O.; Beier, John C.; Troyo Rodríguez (2009-11)
    Temporal behavior of dengue fever and dengue hemorrhagic fever (DH/DHF) has been associated with climate, which may modulate mosquito vector populations. El Niño Southern Oscillation (ENSO) fluctuations can be related to ...
  • Optimización de un método colorimétrico para la cuantificación de cobre en suero 

    García, Mario; Holst Schumacher, Ileana; Schosinsky Nevermann, Karl; Rodríguez, Rocío (1993)
    Se optimizó y adaptó un método colorimétrico para la determinación de cobre sérico con dibenzilditiocarbamato de zinc. El método presenta linealidad por lo menos hasta 400 ug/dl de cobre. La recuperación promedio obtenida ...
  • Neotropical bats that co-habit with humans function as dead-end hosts for dengue virus 

    Vicente Santos, Amanda; Moreira Soto, Andrés; Soto Garita, Claudio; Chaverri Sánchez, Luis Guillermo; Chaves Ramírez, Andrea; Drexler, Jan Felix; Morales Acuña, Juan Alberto; Alfaro Alarcón, Alejandro; Rodríguez Herrera, Bernal; Corrales Aguilar, Eugenia (2017-05-18)
    Several studies have shown Dengue Virus (DENV) nucleic acids and/or antibodies present in Neotropical wildlife including bats, suggesting that some bat species may be susceptible to DENV infection. Here we aim to elucidate ...
  • Associations between urban structure and Aedes aegypti larval habitats in Puntarenas, Costa Rica 

    Troyo Rodríguez, Adriana; Arheart, Kristopher L.; Fuller, Douglas O.; Calderón Arguedas, Ólger; Beier, John C. (2008-12)
    Geospatial technologies have been increasingly applied to study vector-borne diseases, although their use in urban setting has been limited. In this study, high-resolution satellite imagery from QuickBird was analyzed to ...
  • Cuantificación espectrofotométrica del cloruro en suero mediante reacción con tiocianato de mercurio 

    Schosinsky Nevermann, Karl; Chaves Chavarría, Alicia; Jiménez Díaz, Manuel; Holst Schumacher, Ileana; Cox Alvarado, Frank; Mora Castro, Zaida; Valverde Núñez, Sandra (1995)
    El anión que se encuentra en mayor concentración en el fluido extracelular es el ion cloruro (i) (2), por lo que juega un papel importante en regular la distribución del agua, la presión osmótica y el balance aniónico-catiónico ...
  • Determinación del Dímero D en pacientes con anticoagulante lúpico 

    Salazar Sánchez, Lizbeth; Jiménez Bonilla, Rafael; Holst Schumacher, Ileana; Madrigal, Fernando; Fonsecaz, Jorge (1997)
    La determinación del dímero D es de gran utilidad para establecer el diagnóstico de trombosis venosa profunda; sin embargo, en los pacientes que presentan anticoagulante lúpico su hallazgo e importancia todavía no ha sido ...
  • A geographical sampling strategy for field surveys in an urban area using high-resolution satellite imagery 

    Troyo Rodríguez, Adriana; Fuller, Douglas O.; Calderón Arguedas, Ólger; Beier, John C. (2006-11)
    Field evaluations for studying the epidemiology of vector-borne diseases like dengue in urban areas are often restricted to selection of households and buildings for field surveys. Therefore, the resulting sampling frame ...
  • Evaluation of predictive maps for Aedes aegypti larval habitats in two urban areas of Costa Rica 

    Troyo Rodríguez, Adriana; Calderón Arguedas, Ólger; Avendaño López, Adrián; Mora Pineda, Geovanny; Beier, John C.; Fuller, Douglas O. (2011-12)
    The abundance of Aedes aegypti can be associated with urban structure and tree cover, which conceals and protects containers. The purpose of this study was to create and evaluate predictive maps for Ae. Aegypti larval ...
  • Epidemiological characterization of incident cases of Rickettsia infection in rural areas of Urabá region, Colombia 

    Quintero Vélez, Juan Carlos; Aguirre Acevedo, Daniel Camilo; Rodas González, Juan David; Arboleda, Margarita; Troyo Rodríguez, Adriana; Vega Aguilar, Francisco; Osorio Quintero, Lisardo; Rojas Arbeláez, Carlos (2018-10-31)
    Introduction Most of the studies related to rickettsial infection in Colombia are cross-sectional because of the challenge in conducting prospective studies on infectious disease that may have a difficult diagnosis. Although ...
  • Biological and proteolytic variation in the venom of Crotalus scutulatus scutulatus from Mexico 

    Borja, Miguel; Neri Castro, Edgar; Castañeda Gaytán, Gamaliel; Strickland, Jason L.; Parkinson, Christopher L.; Castañeda Gaytán, Juan; Ponce López, Roberto; Lomonte, Bruno; Olvera Rodríguez, Alejandro; Alagón Cano, Alejandro; Pérez Morales, Rebeca (2018-01)
    Rattlesnake venoms may be classified according to the presence/absence and relative abundance of the neurotoxic phospholipases A2s (PLA2s), such as Mojave toxin, and snake venom metalloproteinases (SVMPs). In Mexico, ...
  • Intravascular hemolysis induced by phospholipases A2 from the venom of the Eastern coral snake, Micrurus fulvius: functional profile of hemolytic and non-hemolytic isoforms 

    Fernández Montes de Oca, María Laura; Lomonte, Bruno; Yunes Quartino, Pablo J.; Arce Bejarano, Ruth; Fernández Ulate, Julián; Camacho, Luis F.; Gutiérrez, José María; Kuemmel, Daniel; Fidelio, Gerardo Daniel (2018-04)
    A unique feature of the venom of Micrurus fulvius (Eastern coral snake) is its ability to induce severe intravascular hemolysis in particular species, such as dogs or mice. This effect was previously shown to be induced ...
  • Pros and cons of different therapeutic antibody formats for recombinant antivenom development 

    Laustsen, Andreas Hougaard; Gutiérrez, José María; Knudsen, Cecilie; Johansen, Kristoffer H.; Bermúdez Méndez, Erick; Cerni, Felipe A.; Jürgensen, Jonas A.; Ledsgaard, Line; Martos Esteban, Andrea; Øhlenschlæger, Mia; Pus, Urska; Andersen, Mikael Rørdam; Lomonte, Bruno; Engmark, Mikael Gerling; Pucca, Manuela Berto (2018-05)
    Antibody technologies are being increasingly applied in the field of toxinology. Fuelled by the many advances in immunology, synthetic biology, and antibody research, different approaches and antibody formats are being ...
  • Proteomic and toxinological characterization of the venom of the South African Ringhals cobra Hemachatus haemachatus 

    Sánchez Brenes, Andrés; Herrera Vega, María; Villalta Arrieta, Mauren; Solano, Daniela; Segura Ruíz, Álvaro; Lomonte, Bruno; Gutiérrez, José María; León Montero, Guillermo; Vargas Arroyo, Mariángela (2018-06)
    The protein composition and toxinological profile of the venom of the African spitting elapid Hemachatus haemachatus (Ringhals) were characterized by bottom-up proteomics and functional in vitro and in vivo assays. Venom ...
  • Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms 

    Gutiérrez, José María; Rucavado, Alexandra; Escalante Muñoz, Teresa; Herrera Arias, Cristina; Fernández Ulate, Julián; Lomonte, Bruno; Fox, Jay W. (2018-06)
    Snakebite envenoming by viperid species, and by some elapids, is characterized by a complex pattern of tissue damage at the anatomical site of venom injection. In severe cases, tissue destruction may be so extensive as ...
  • A myotoxic Lys49 phospholipase A2-homologue is the major component of the venom of Bothrops cotiara from Misiones, Argentina 

    de Roodt, Adolfo Rafael; Fernández Ulate, Julián; Solano, Daniela; Lomonte, Bruno (2018-04-27)
    Bothrops cotiara is a pitviper found in Southeastern Brazil and, scarcely, in the Misiones province of Argentina. In contrast to considerable information available on the venom of the Brazilian snake population, that of ...

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