Microbiología
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Analysis of mutational dynamics at the DMPK (CTG)n locus identifies saliva as a suitable DNA sample source for genetic analysis in myotonic dystrophy type 1
(2019-05)Genotype-to-phenotype correlation studies in myotonic dystrophy type 1 (DM1) have been confounded by the age-dependent, tissue-specific and expansion-biased features of somatic mosaicism of the expanded CTG repeat. Previously, ... -
Low-cost internal controls for detection of Giardia cysts in water samples
(2019-08)Giardia cysts stained with hot carbolfuchsin were used as internal controls in a concentration method for surface water samples. The morphological integrity of stained cysts and the stain's stability and intensity were ... -
Leucemia Mieloide Crónica Juvenil. A propósito de un caso
(2019-05-01)La leucemia Mieloide Crónica (LMC) es una neoplasia mieloproliferativa crónica, caracterizada por un gen de fusión t(9,22). El curso normal de la enfermedad consta de 3 fases: crónica, acelerada y blástica. En su gran ... -
Modificaciones proteicas inducidas por Brucella abortus 2308W en compartimentos intracelulares tempranos de macrófagos RAW 264.7
(2019)Brucella abortus es un patógeno intracelular bacteriano causante de la brucelosis bovina, una zoonosis desatendida de gran importancia mundial. Una vez entra a la célula hospedera B. abortus transita en un compartimento ... -
Caracterización proteómica y toxicológica del veneno de Crotalus pifanorum (viperidae) y evaluación de su uso como inmunógeno sobre la respuesta por anticuerpos contra co-inmunógenos y venenos de otros crótalos americanos
(2019)En Costa Rica se produce un antiveneno poliespecífico (PoliVal-ICP) usando como inmunógenos los venenos de las serpientes Bothrops asper, Crotalus simus y Lachesis stenophrys. Este antiveneno es capaz de neutralizar a la ... -
Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920)
(2019)The World Health Organization recently listed snakebite envenoming as a Neglected Tropical Disease, proposing strategies to significantly reduce the global burden of this complex pathology by 2030. In this context, ... -
Interacción de neutrófilos murinos con Brucella abortus
(2019-12)La brucelosis es una enfermedad zoonótica con distribución mundial. La enfermedad se caracteriza por ocasionar fiebre ondulante en humanos y abortos en animales domésticos como vacas, ovejas, cabras, cerdos y perros. ... -
ENSO‐Influenced Drought Drives Methane Flux Dynamics in a Tropical Wet Forest Soil
(2019)Global atmospheric methane growth rates have wildly fluctuated over the past three decades, which may be driven by the proportion of tropical land surface saturated by water. The El Niño/Southern Oscillation Event (ENSO) ... -
Community richness of amphibian skin bacteria correlates with bioclimate at the global scale
(2019)Animal-associated microbiomes are integral to host health, yet key biotic and abiotic factors that shape host-associated microbial communities at the global scale remain poorly understood. We investigated global patterns ... -
Ant microbial symbionts are a new model for drug discovery
(2019)Ants have been widely studied, with 14,000 described species, but it is not until recently that they gained attention as sources for antimicrobial drug discovery. An increasing amount of studies are investigating ant-microbe ... -
Welcome to the Atta world: A framework for understanding the effects of leaf‐cutter ants on ecosystem functions
(2019)1. Leaf‐cutter ants are a prominent feature in Neotropical ecosystems, but a comprehensive assessment of their effects on ecosystem functions is lacking. We reviewed the literature and used our own recent findings to ... -
Assessment of microbial communities associated with the gut and feeding substrate of three xylophagous coleopteran families with emphasis on cellulose-degrading bacteria
(2019-11)The current energy crisis and depletion of fossil fuel reserves has encouraged research for new alternatives. Degradation of plant material by enzymatic reactions represents an important strategy to obtain affordable and ... -
Phylogenetic analyses of antibiotic-producing Streptomyces sp. isolates obtained from the stingless-bee Tetragonisca angustula (Apidae: Meliponini)
(2019)Many insects have been associated with actinobacteria in protective symbiosis where antimicrobial metabolites inhibit host pathogens. However, the microbiota of neotropical insects such as the stingless-bee Tetragonisca ... -
Detección del virus del oeste del Nilo en dos localidades con antecedentes de enfermedad neurológica en equinos: determinación molecular en aves y mosquitos y serología en humanos, aves y equinos
(2019-11)El virus de Oeste del Nilo (WNV por sus siglas en inglés) es un miembro de la familia Flaviviridae. Su ciclo natural involucra la transmisión entre aves y mosquitos. Las aves son los hospederos y diseminadores del patógeno ... -
Population Genomics Insights into Adaptive Evolution and Ecological Differentiation in Streptomycetes
(2019)Deciphering the genomic variation that represents microevolutionary processes toward species divergence is key to understanding microbial speciation, which has long been under debate. Streptomycetes are filamentous bacteria ... -
The antimicrobial potential of Streptomyces from insect microbiomes
(2019)Antimicrobial resistance is a global health crisis and few novel antimicrobials have been discovered in recent decades. Natural products, particularly from Streptomyces, are the source of most antimicrobials, yet discovery ... -
The Role of the Ecosystem Engineer, the Leaf-Cutter Ant Atta cephalotes, on Soil CO2 Dynamics in a Wet Tropical Rainforest
(2019)Leaf‐cutter ants are dominant herbivores that disturb the soil and create biogeochemical hot spots. We studied how leaf‐cutter ant Atta cephalotes impacts soil CO2 dynamics in a wet Neotropical forest. We measured soil CO2 ... -
The sexist beliefs that underlie in the pedagogy about obesity in physical education classes
(2019)The physical education class and the teachers guide to this subject are key elements to make physical activity a habit for life. This article describes the sexist beliefs that underlie in the pedagogy about obesity in ... -
Socio-Demographic, Biopsychosocial and Lifestyle behaviors related with eating disorders of children and adolescents of Costa Rica
(2019)The objective of the study was to evaluate the association of sociodemographic, biopsychosocial and lifestyle behaviors (diet, sedentarism and physical activity) with eating disorders (ED) in a national sample of Costa ... -
Bioprospección de beta-glucosidasas novedosas a partir de metagenomas obtenidos de intestinos de escarabajos pasálidos de Costa Rica y respiraderos hidrotermales de la Isla Vulcano en Italia
(2019-10)La aplicación de tecnologías que permitan el establecimiento de biorrefinerías constituye una alternativa interesante que busca incentivar una menor dependencia en el uso de combustibles fósiles y generar productos de valor ...
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