Synthesis of 2-hydroxy-3-substituted naphthoquinones using the Heck reaction
Pérez Sánchez, Alice Lorena
Lamoureux Lamontagne, Guy
Zhen-Wu, Bi Yun
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An efficient Heck coupling of 2-hydroxy-3-iodo-naphthoquinone with a series of electron-deficient alkenes in aqueous solution has been accomplished. The method is characterized by simple conditions and facile work-up to isolate the products in good to excellent yields. The products contain the motif present in several naphthoquinone pigments but with enhanced polarity.
External link to the item10.1016/j.tetlet.2007.04.033
- Química