Does genetic variation in the Δ6-desaturase promoter modify the association between α-linolenic acid and the prevalence of metabolic syndrome?
Loading...
Date
Authors
Truong, Hong
DiBello, Julia R.
Ruiz Narváez, Edward A.
Kraft, Peter
Campos Núñez, Hannia
Baylin, Ana
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background: Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are associated with protection against components of the metabolic syndrome, but the role of α-linolenic acid (ALA), the metabolic precursor of EPA and DHA, has not been studied. The Δ6-desaturase enzyme converts ALA into EPA and DHA, and genetic variation in the Δ6-desaturase gene (FADS2) may affect this conversion.
Description
Keywords
Enfermedades cardiovasculares, Metabolismo
Citation
https://academic.oup.com/ajcn/article/89/3/920/4596766?searchresult=1