Listar Investigación por autor "IJzermans, Jan N. M."

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    • Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors 

      Pedroza González, Alexander; Zhou, Guoying; Vargas Méndez, Ernesto; Boor, Patrick P.C.; Mancham, Shanta; Verhoef, Cornelis; Polak, Wojciech G.; Grünhagen, Dirk; Pan, Qiuwei; Janssen, Harry L. A.; García Romo, Gina S.; Biermann, Katharina; Tjwa, Eric T. T. L.; IJzermans, Jan N. M.; Kwekkeboom, Jaap; Sprengers, Dave (2015-10-01)
      CD4C type 1 T regulatory (Tr1) cells have a crucial role in inducing tolerance. Immune regulation by these cells is mainly mediated through the secretion of high amounts of IL-10. Several studies have suggested that this ...