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Cyclin-dependent kinase 4/6 inhibitors as first-line treatment for post-menopausal metastatic hormone receptor-positive breast cancer patients: a systematic review and meta-analysis of phase III randomized clinical trials.
(2018)
Background
To compare the efficacy and toxicity of the combination of cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors and nonsteroidal aromatase inhibitors (AI) versus AI alone as first-line therapy for patients with ...
Mapping estuarine vegetation using satellite imagery: The case of the invasive species Baccharis halimifolia at a Natura 2000 site
(2019-02)
The invasive shrub Baccharis halimifolia is a threat to the environmental health of many estuarine protected areas
throughout Europe. It displaces saltmarsh vegetation and creates monospecific stands that diminish the ...
Poder y alternativas: las agendas internacionales en las reformas del sector salud en Costa Rica, 1988-1998
(1999)
Este trabajo examina dos políticas de reforma de la salud llevadas a cabo consecutivamente en Costa Rica entre 1988 y 1998. A partir de datos de entrevistas y otros documentos, este trabajo argumenta que actores a los que ...
Monte Carlo dosimetry of a realistic multicellular model of follicular lymphoma in a context of radioimmunotherapy
(2020)
Purpose
Small-scale dosimetry studies generally consider an artificial environment where the tumors are spherical and the radionuclides are homogeneously biodistributed. However, tumor shapes are irregular and radiopharmaceutical ...
Physiological wear-and-tear and later subjective health in mid-life: Findings from the 1958 British birth cohort
(2016)
Our body adapts continuously to environmental challenges and stressful conditions. Allostatic load (AL) is a concept that aims to capture the overall physiological wear-and-tear of the body triggered by the repeated ...
Modelling SPECT auto-contouring acquisitions for 177Lu & 131I molecular radiotherapy using new developments in Geant4/GATE
(2022)
Purpose
Monte Carlo modelling of SPECT imaging in Molecular Radiotherapy can improve activity quantification. Until now, SPECT modelling with GATE only considered circular orbit (CO) acquisitions. This cannot reproduce ...
A sustainable lignocellulosic biodiesel production integrating solar- and bio-power generation
(2016-06-04)
A solar-bio-powered refining concept has been developed to establish sustainable lignocellulosic biodiesel production. The refining concept applies a combined hydrolysis process without detoxification to release sugars ...
Detection of Potyvirus-like Particles Associated with Oil Palms (Elaeis guineensis) in Ecuador
(1996-09-03)
Oil palm (Elaeis guineensis Jacq.) seedlings showing a conspicuous mottling, composed of alternating dark green and chlorotic areas in the form of discontinuous streaks or irregular ring patterns, were observed in the ...
Presión o legitimación: poder y alternativas en el diseño y adopción de la reforma de salud de Costa Rica, 1988-1999
(2006)
La formación de políticas responde a lógicas de presión y legitimación que se combinan de distintas maneras. Este trabajo analiza el diseño y adopción de dos políticas de reforma de salud realizadas en Costa Rica entre ...
Condensación de Cetonas Alifáticas con la Fenantrenoquinona en Hidróxido de Amonio
(1971)
A study on the synthesis and structure of the products of condensation of phenanthrenequinone with acetone and methyl-ethyl-ketone in presence of ammonia was
made. The structures were established by spectroscopic methods. ...