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Inflammatory events induced by Lys-49 and Asp-49 phospholipases A2 isolated from Bothrops asper snake venom: role of catalytic activity
(2005-03)The inflammatory events induced in the peritoneal cavity of mice by two PLA2s isolated from Bothrops asper snake venom were investigated. MT-III, an Asp-49 catalytically active enzyme and MT-II, a catalytically inactive ... -
Influence of Mild Dehydration on Exercise Performance
(2001-12)This presentation summarizes some initial evidence for an impairment of exercise performance due to mild dehydration. An attempt is made at defining mild dehydration, and preliminary hypotheses are presented. -
Influence of Orally Administered Antibiotics on Faecal pH and Volatile Fatty Acid Concentrations on Infants and Young Children
(1990)Faecal specimens were collected from infants and children with common infections who presented to the Paediatrics Outpatient Department of the National Children's Hospital, San Jose, Costa Rica or to the Paediatrics Clinic, ... -
Influence on the growth parameters of children
(Raven Press p 85-94, 1983)The close interactions between toxin-producing bacterial agents and the host in cases of diarrhea are reflected in several significant physiologic and nutritional alterations. The negative nutritional effects of diarrhea ... -
Influencia del uso del suelo en la calidad del agua en la subcuenca del río Jabonal, Costa Rica
(2006-08)La subcuenca del río Jabonal, Costa Rica, se caracteriza por el predominio de extensas áreas dedicadas a la producción ganadera. Se seleccionaron ocho microcuencas y se evaluó la calidad del agua a través de análisis ... -
Inhibition by CaNa2EDTA of local tissue damage induced by Bothrops asper (terciopelo) venom: Application in horse immunization for antivenom production
(1998-03-26)The ability of the chelating agent CaNa2EDTA to inhibit local tissue damage induced by Bothrops asper venom was studied in mice and in horses used for polyvalent (Crotalinae) antivenom production. CaNa2EDTA was devoid of ... -
Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom: effectiveness of early in situ administration of the peptidomimetic metalloproteinase inhibitor batimastat and the chelating agent CaNa2EDTA
(2000-11)The effectiveness of the chelating agent CaNa2EDTA and the peptidomimetic matrix metalloproteinase inhibitor batimastat (BB-94) to inhibit local tissue damage induced by Bothrops asper snake venom was studied in mice. Both ... -
Inhibition of Myotoxic Activity of Bothrops asper Myotoxin II by the Anti-trypanosomal Drug Suramin
(2005-06-15)Suramin, a synthetic polysulfonated compound, developed initially for the treatment of African trypanosomiasis and onchocerciasis, is currently used for the treatment of several medically relevant disorders. Suramin, ... -
Inhibition of the hemorrhagic activity of Bothrops asper venom by a novel neutralizing mixture
(1997-06)This study screened 25 sera, 19 synthetic products and five antivenoms obtained after immunization for their ability to neutralize the hemorrhagic activity of venom from the snake Bothrops asper. Among the sera screened, ... -
Inhibition of the myotoxic activity of Bothrops aspermyotoxin II in mice by immunization with its synthetic 13-mer peptide 115-129
(1999)The region comprising amino acid residues 115±129 of myotoxin II, a Lys49 phospholipase A2 from the venom of Bothrops asper, was previously shown to constitute a heparin binding site, and to be associated with its toxic ... -
Inhibition of toxic activities of Bothrops asper venom and other crotalid snake venoms by a novel neutralizing mixture
(1997-12)The majority of snake bites in Central America are caused by Bothrops asper, whose venom induce complex local effects such as myonecrosis, edema and especially hemorrhage. These effects are only partially neutralized by ... -
Inhibitory effect of fucoidan on the activities of crotaline snake venom myotoxic phospholipases A2
(2003)Myotoxic phospholipases A2 account for most of the muscle necrosis that results from envenenomation by crotaline snakes. In this study, we investigated the protective effect of fucoidan, a natural sulfated polysaccharide ... -
Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: isolation of 4-nerolidylcatechol as active principle
(2005)Phospholipases A2 (PLA2) are important constituents of snake venoms, being responsible for several of their toxic actions. Extracts from plants used in folk medicine were screened for inhibition of the enzymatic activity ... -
Injerto capilar como tecnica reconstructiva en alopecia cicatricial posterior a trauma
(2020-08-11)Resumen La pérdida de cabello por cicatrices secundarias a traumatismo es una secuela que muchas veces se toma a la ligera por los cirujanos reconstructivos, dejando a muchos pacientes sin la oportunidad de mejorar ... -
Inmunización con la vacuna de la gripe durante el II y III trimestre de embarazo comparado con la no inmunización y su relación con el riesgo de complicaciones fetales
(2019)Las acciones profesionales obstétricas y criterios para la aplicación de la vacuna contra la influenza durante el embarazo varían ampliamente entre los diferentes países, entre las diferentes instituciones nacionales y los ... -
Innovación en la producción microempresaria de cosméticos de leche de cabra en la universidad de Costa Rica
(2015)Desde el año 2009 la Universidad de Costa Rica por medio de la Facultad de Farmacia se ha dedicado a promover un modelo de desarrollo en la pequeña y mediana industria cosmética, para las zonas rurales o más pobres de Costa ... -
Innovation in the production of a cream based on thermal waters from the surroundigs of the Arenal Volcano in Costa Rica
(2015)Introduction: Since 2009 the University of Costa Rica, through the Faculty of Pharmacy, is dedicated to promote a model of development in cosmetics in small and medium industries in rural or poorest areas of Costa Rica, ... -
Innovative immunization strategies for antivenom development
(2018)Snakes, scorpions, and spiders are venomous animals that pose a threat to human health, and severe envenomings from the bites or stings of these animals must be treated with antivenom. Current antivenoms are based on ...