Listar Investigación por autor "Heidersdorf, B."
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The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling
De Ford, Christian; Heidersdorf, B.; Haun, F.; Merfort, Irmgard; Murillo Masís, Renato; Friedrich, T.; Borner, C. (2016-01-28)T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy that preferentially affects children and adolescents. Over 50% of human T-ALLs possess activating mutations of Notch1. The clerodane ...