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Mostrando ítems 374-393 de 4024
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Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper
(2024)Improved therapies are needed against snakebite envenoming, which kills and permanently disables thousands of people each year. Recently developed neutralizing monoclonal antibodies against several snake toxins have ... -
Antibody-mediated neutralization and binding-reversal studies on α-neurotoxins from micrurus nigrocinctus nigrocinctus (coral snake) venom
(1996-03)An ELISA based, non-radioactive acetylcholine receptor (AchR) binding assay was used to detect the alpha-neurotoxins present in Micrurus nigrocinctus nigrocinctus venom. Sera from horses hyperimmunized against M. nigrocinctus ... -
Anticoagulación Oral Periprocedimiento en el Adulto Mayor: Propuesta de Abordaje del Paciente Ambulatorio y Hospitalizado
(2022)En los últimos años el número de pacientes adultos mayores que requieren anticoagulación oral con antagonistas de la vitamina K o anticoagulantes se acción directa, está aumentando significativamente, ... -
Anticomplementary activity of equine whole IgG antivenoms: comparison of three fractionation protocols
(2005-01)Early adverse reactions occur in a number of patients treated with heterologous antivenoms and have been associated with anticomplementary activity (ACA). In order to reduce the ACA of equine whole IgG antivenoms produced ... -
Anticomplementary Activity of Horse IgG and F(ab’)2 Antivenoms
(2014)Envenomation by poisonous animals is a neglected condition according to the World Health Organization (WHO). Antivenoms are included in the WHO Essential Medicines List. It has been assumed that immunoglobulin G (IgG) ... -
Anticuerpos IgE específicos de alergenos comunes en niños costarricenses
(Alergia, Asma e Inmunología Pediátricas :13 (2); p 40-43, 2004-05)La morbilidad por asma y otras enfermedades alérgicas aumentan cada año y un factor muy importante es la exposición a niveles elevados de alergenos interiores. En el presente estudio se evaluó la prevalencia y la exposición ... -
Anticuerpos monoclonales y el tratamiento del lupus eritematoso sistémico.
(2021)El lupus eritematoso sistémico es una enfermedad autoinmune crónica, que implica la producción de ciertos anticuerpos en todo el cuerpo y la consecuente inflamación de tejidos conjuntivos, así como afecciones cutáneas, ... -
Antidepressant imipramine diminishes stress-induced inflammation in the periphery and central nervous system and related anxiety- and depressive- like behaviors
(2016)In order to relieve anxiety and depression accompanying stress, physicians resort to tricyclic antidepressants, such as imipramine. We had previously shown that imipramine reversed stress-induced social avoidance behavior, ... -
Antiinflamatorios no esteroidales (AINEs)
(2001)En los pasados 100 años, la aspirina ha demostrado su valor como analgésico, antiinflamatorio y antitrombótico. Sin embargo, para el año de 1938 quedó bien establecida la gastrotoxicidad de la misma. Y aunque en la década ... -
Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region
(2005)A short peptide derived from the C-terminal region of Bothrops asper myotoxin II, a Lys49 phospholipase A2 (PLA2), was previously found to reproduce the bactericidal activity of its parent molecule. In this study, a panel ... -
Antioxidant and Anti-inflammatory in Vitro Activities of Phenolic Compounds from Tropical Highland Blackberry (Rubus adenotrichos)
(2013-05-22)This study evaluates the antioxidant and anti-inflammatory activities in a polyphenol extract from blackberries. The antioxidant activity measured via oxygen radical absorbance capacity (ORAC) was higher for the blackberry ... -
Antiplasmodial effect of the venom of Crotalus durissus cumanensis, crotoxin complex and Crotoxin B
(2012-11)The antiplasmodial activity of phospholipases A2 (PLA2) isolated from different animals has been studied. We explored the in vitro anti Plasmodium falciparum effect of a fraction containing crotoxin, Crotoxin B and whole ... -
Antitumor effects of cationic synthetic peptides derived from Lys49 phospholipase A2 homologues of snake venoms
(2007)The effects of two cationic synthetic peptides, derived from the C-terminal region of Lys49 phospholipase A2 homologues from snake venoms, upon various murine tumor cell lines (B16 melanoma, EMT6 mammary carcinoma, S-180 ... -
Antivenom for snakebite envenoming in Sri Lanka: The need for geographically specific antivenom and improved efficacy
(2013-07)Sri Lanka is a tropical developing island nation that endures significant economic and medical burden as a result of snakebite envenomation, having not only a high prevalence of envenomations, but also one of the highest ... -
Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa
(2010)The immunoreactivity of EchiTAb-Plus-ICP, an antivenom developed for the treatment of snakebite envenoming in sub-Saharan Africa, to venoms of seven Echis and Bitis species, was assessed by “antivenomics.” This proteomic ... -
Antivenomic Characterization of Two Antivenoms Against the Venom of the Taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia
(2014-11-05)Antivenoms manufactured by bioCSL Limited (Australia) and Instituto Clodomiro Picado (Costa Rica) against the venom of the taipan snakes (Oxyuranus scutellatus) from Australia and Papua New Guinea (PNG), respectively, were ... -
Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms
(2021)Snakebite envenoming is an important occupational health problem, particularly in rural areas of developing countries. The timely administration of an effective antivenom remains the mainstay of snakebite management. ... -
Antivenomics of Atropoides mexicanus and Atropoides picadoi snake venoms: Relationship to the neutralization of toxic and enzymatic activities
(2010-09-30)Viperid snakes of the genus Atropoides are distributed in Mexico and Central America and, owing to their size and venom yield, are capable of provoking severe envenomings in humans. This study evaluated, using an ‘antivenomics’ ... -
Antivenomics: a proteomics tool for studying the immunoreactivity of antivenoms
(2015-03)Envenoming following snakebite is largely a neglected threat to public health in tropical and subtropical regions of Africa, Asia, Latin America and Oceania addicting some of the world’s poorest rural communities. An ... -
Antivenoms for Snakebite Envenomings
(2011-10)Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming. Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a single or several medically-relevant snake ...