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Snake venomics of the pit vipers Porthidium nasutum, Porthidium ophryomegas, and Cerrophidion godmani from Costa Rica: Toxicological and taxonomical insights
(2012-02-16)
Within the Neotropical pit vipers, a lineage of primarily Middle American snake species
referred to as the “Porthidium group” includes the genera Atropoides, Cerrophidion, and
Porthidium. In this study, the venom proteomes ...
Venom of the Coral Snake Micrurus clarki: Proteomic Profile, Toxicity, Immunological Cross-Neutralization, and Characterization of a Three-Finger Toxin
(2016)
Micrurus clarki is an uncommon coral snake distributed from the Southeastern Pacific of Costa Rica to Western Colombia, for which no information on its venom could be found in the literature. Using a 'venomics' approach, ...
Primary structures and partial toxicological characterization of two phospholipases A2 from Micrurus mipartitus and Micrurus dumerilii coral snake venoms
(2017-06)
Snake venom phospholipases A2 (PLA2) share high sequence identities and a conserved structural scaffold, but show important functional differences. Only a few PLA2s have been purified and characterized from coral snake ...
Antibodies against a single fraction of Micrurus dumerilii venom neutralize the lethal effect of whole venom
(2023-02-01)
The coralsnake Micrurus dumerilii (Elapidae) is reported to cause envenomings of medical importance. Previous studies characterized the protein composition of its venom, with phospholipase A2 (PLA2) proteins the most ...
Mipartoxin-I, a novel three-finger toxin, is the major neurotoxic component in the venom of the redtail coral snake Micrurus mipartitus (Elapidae)
(2012)
The major venom component of Micrurus mipartitus, a coral snake distributed from
Nicaragua to northern South America, was characterized biochemically and functionally.
This protein, named mipartoxin-I, is a novel member ...
Venoms of Micrurus coral snakes: evolutionary trends in compositional patterns emerging from proteomic analyses
(2016-11)
The application of proteomic tools to the study of snake venoms has led to an impressive growth in the
knowledge about their composition (venomics), immunogenicity (antivenomics), and toxicity (toxicovenomics).
About ...
Proteomic and biological characterization of the venom of the redtail coral snake, Micrurus mipartitus (Elapidae), from Colombia and Costa Rica
(2011-12)
Venoms of the redtail coral snake Micrurus mipartitus from Colombia and Costa Rica were
analyzed by “venomics”, a proteomic strategy to determine their composition. Proteins
were separated by RP-HPLC, followed by SDS-PAGE, ...
Novel three-finger toxins from Micrurus dumerilii and Micrurus mipartitus coral snake venoms: phylogenetic relationships and characterization of Clarkitoxin-I-Mdum
(2019)
Micrurus mipartitus and M. dumerilii are the most medically important coral snakes in Colombia. Proteomic
characterization of their venoms has previously shown that proteins of the three-finger toxin (3FTx) family ...
Immunological cross-recognition and neutralization studies of Micrurus mipartitus and Micrurus dumerilii venoms by two therapeutic equine antivenoms
(2020)
New world Coral snakes comprise 82 species of medical importance distributed from southeastern United States to Argentina. In Colombia, Micrurus mipartitus and M. dumerilii are responsible for most coral snakebite accidents. ...
Integrative characterization of the venom of the coral snake Micrurus dumerilii (Elapidae) from Colombia: proteome, toxicity, and cross-neutralization by antivenom
(2016-03)
In Colombia, nearly 2.8% of the 4200 snakebite accidents recorded annually are inflicted by coral snakes (genus
Micrurus). Micrurus dumerilii has a broad distribution in this country, especially in densely populated ...