ListarQuímica por tema "Inhibition"

Mostrando ítems 1-2 de 2

    • Baulamycins A and B, Broad-Spectrum Antibiotics Identified as Inhibitors of Siderophore Biosynthesis in Staphylococcus aureus and Bacillus anthracis 

      Tripathi, Ashootosh; Schofield, Michael M.; Chlipala, George E.; Schultz, Pamela J.; Yim, Isaiah; Newmister, Sean A.; Nusca, Tyler D.; Scaglione, Jamie B.; Hanna, Philip C.; Tamayo Castillo, Giselle; Sherman, David H. (2014)
      Siderophores are high-affinity iron chelators produced by microorganisms and frequently contribute to the virulence of human pathogens. Targeted inhibition of the biosynthesis of siderophores staphyloferrin B of Staphylococcus ...

    • Norstictic Acid Is a Selective Allosteric Transcriptional Regulator 

      Garlick, Julie M.; Sturlis, Steven M.; Bruno, Paul A.; Yates, Joel A.; Peiffer, Amanda L.; Liu, Yejun; Goo, Laura; Bao, LiWei; De Salle, Samantha N.; Tamayo Castillo, Giselle; Brooks, Charles L. III; Merajver, Sofia D.; Mapp, Anna K. (2021-06-17)
      Inhibitors of transcriptional protein–protein interactions (PPIs) have high value both as tools and for therapeutic applications. The PPI network mediated by the transcriptional coactivator Med25, for example, regulates ...