Carcinoma de células escamosas basaloide en paladar: Reporte de caso
Fecha
2017
Tipo
artículo original
Autores
Boza Oreamuno, Yadira Vanessa
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ISSN de la revista
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Resumen
El carcinoma de células escamosas basaloide (CCEB) es una variante poco común y agresiva del
carcinoma de células escamosas (CCE), con predilección por el tracto aerodigestivo superior, siendo el
paladar un sitio muy raro de desarrollo. Está constituido por un componentes basaloide y uno escamoso
en proporciones variables, sin embargo, las características histopatológicas del CCEB se superponen
con otras neoplasias. El diagnóstico con diversos marcadores inmunohistoquímicos como p63, Ki67,
p16, y citoqueratinas AE1 / AE3 se han convertido en una necesidad para el especialista. El objetivo de
este trabajo es presentar un caso de CCEB en paladar blando y evidenciar la importancia del apoyo en
la inmunohistoquímica para un diagnóstico histopatológico precoz. Se presenta además una revisión de
literatura en cuanto a esta patología
Basaloid Squamous Cell Carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma (SCC), with a predilection for the upper aerodigestive tract, the palate being a very rare site of development. It is constituted by a basaloid and a squamous components in variable proportions, however, the histopathological characteristics of the BSCC overlap with other neoplasias. Diagnosis with various immunohistochemical markers such as p63, Ki67, p16, and AE1 / AE3 cytokeratins have become a necessity for the specialist. The objective of this study is to present a case of BSCC in soft palate and to show the importance of the support in the immunohistochemistry for an early histopathological diagnosis. A review of the literature on this pathology is also presented.
Basaloid Squamous Cell Carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma (SCC), with a predilection for the upper aerodigestive tract, the palate being a very rare site of development. It is constituted by a basaloid and a squamous components in variable proportions, however, the histopathological characteristics of the BSCC overlap with other neoplasias. Diagnosis with various immunohistochemical markers such as p63, Ki67, p16, and AE1 / AE3 cytokeratins have become a necessity for the specialist. The objective of this study is to present a case of BSCC in soft palate and to show the importance of the support in the immunohistochemistry for an early histopathological diagnosis. A review of the literature on this pathology is also presented.
Descripción
Palabras clave
Carcinoma de células escamosas basaloide, Cavidad oral, Carcinoma de células escamosas, Inmunohistoquímica, Basaloid squamous cell carcinoma, Oral cavity, Squamous cell carcinoma, Immunohistochemistry