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Efficacy of Endodontic Treatment on the Persistence of Selected Endodontic Pathogens and on Radiographical Periapical Healing

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dc.creatorZeledón Mayorga, Rodolfo
dc.creatorBallestero, Carolina
dc.creatorHernández, Erick
dc.creatorRamírez Mora, Tatiana
dc.creatorBenavides García, Marianella
dc.creatorMeneses Guzmán, José Pablo
dc.creatorReyes Carmona, Jessie
dc.creatorSilva de la Fuente, Sandra Maria
dc.date2015-12-01
dc.date.accessioned2016-05-02T22:19:08Z
dc.date.available2016-05-02T22:19:08Z
dc.descriptionThe objective of this clinical study was to evaluate by polymerase chain reaction (PCR) the antimicrobial efficacy and the outcome of an endodontic protocol treatment (EPT) performed by under-graduated dental students on infected root canals associated with periapical lesions. Fifty-six patients attending for treatment of pulp necrosis and apical periodontitis were included. A specific EPT approach was performed and DNA extracts were taken at the baseline (S1), after a disinfection-neutralization procedure (S2), post-chemomechanical preparation (S3) and after Intracanal medication (S4) for the presence of specific bacteria. The outcome of the EPT was assessed radiographically using the Periapical Index-system (PAI) after 18-month follow-up. An intergroup evaluation shows that when comparing S1 to S3, S1 to S4, S2 to S3, and S2 to S4, the presence of bacteria were significantly reduced (P < 0.05). Finally, S4 was not significantly reduced when compared with S3 (P > 0.05). The most prevalent species in their respect order were Actinomyces Israelii > Enterococcus Faecalis > Fusobacterium Nucleatum/Prevotella Nigrescens > Phorphyromonas Endodontalis. After the 18-month follow-up, the overall success rate of root canal – treated teeth was of 88% (PAI 1 or 2). This In Vivo study demonstrated that EPT significantly reduced the number of cases with positive results for the studied bacteria, showing a profound positive impact in the outcome of endodontic treatment of teeth diagnosed with Pulp Necrosis and Apical Periodontitis. en-US
dc.formatapplication/pdf
dc.identifierhttp://revistas.ucr.ac.cr/index.php/Odontos/article/view/22035
dc.identifier10.15517/ijds.v0i0.22035
dc.identifier.urihttps://hdl.handle.net/10669/21348
dc.languageeng
dc.publisherUniversidad de Costa Ricaen
dc.rightsacceso abierto
dc.sourceOdovtos - International Journal of Dental Sciences; Vol 17, No 2 (2015): Odovtos - International Journal of Dental Sciences V.17, 2; 41-50en
dc.source2215-3411
dc.source1659-1046
dc.source10.15517/ijds.v17i2
dc.titleEfficacy of Endodontic Treatment on the Persistence of Selected Endodontic Pathogens and on Radiographical Periapical Healingen
dc.typeartículo original

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Odovtos 17(2)