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An alternative in vitro method for testing the potency of the polyvalent antivenom produced in Costa Rica

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dc.creatorGutiérrez, José María
dc.creatorÁvila Agüero, Claudio
dc.creatorCerdas Fallas, Luis
dc.creatorRojas Umaña, Ermila
dc.creatorCerdas Fallas, Luis
dc.date.accessioned2016-11-07T16:16:36Z
dc.date.available2016-11-07T16:16:36Z
dc.date.issued1988
dc.description.abstractThe ability of several batches of polyvalent antivenom to neutralize indirect hemolytic activity of Bothrops asper venom was studied using a sensitive plate test. All samples of antivenom tested effectively neutralized this activity. A highly significant correlation was observed between neutralization of indirect hemolysis and neutralization of lethal activity. This simple and sensitive in vitro test could be used to monitor antibody levels in horses immunized to produce polyvalent antivenom.es_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/0041010188900104
dc.identifier.doi10.1016/0041-0101(88)90010-4es_ES
dc.identifier.issn0041-0101
dc.identifier.urihttps://hdl.handle.net/10669/29152
dc.language.isoen_USes_ES
dc.rightsacceso embargado
dc.sourceToxicon; Volumen 26, Número 4, 1988es_ES
dc.subjectAnimalses_ES
dc.subjectAntiveninses_ES
dc.subjectCosta Ricaes_ES
dc.subjectCrotalid Venomses_ES
dc.subjectHemolysises_ES
dc.subjectDrug Effectses_ES
dc.subjectHorseses_ES
dc.subjectImmunologyes_ES
dc.subjectIn Vitro Techniqueses_ES
dc.subjectMicees_ES
dc.subjectNeutralization Testses_ES
dc.subjectSnake venomes_ES
dc.titleAn alternative in vitro method for testing the potency of the polyvalent antivenom produced in Costa Ricaes_ES
dc.typeartículo original

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