Niveles de inmunoglobulinas séricas (IgG, IgA e IgM) en adultos jóvenes sanos, por el método de inmunodifusión radial
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Lomonte, Bruno
Bonilla, César
Castro, Elizabeth
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Abstract
Se determinó la concentración de IgG, IgA, e IgM en el suero de 49 estudiantes universitarios normales, de 18 a 25 años. Para esto se empleó el método de inmunodifusión radial, en placas comerciales. Los resultados fueron comparados con una serie de valores descritos en la literatura, correspondientes a niveles normales en distintos países. Se encontró que los valores de IgG son ligeramente mayores, mientras que los de IgA e IgM son similares a los descritos en otras poblaciones. Se comenta brevemente las alternativas metodológicas existentes para la cuantificación de Igs séricas, así como algunos aspectos de la estandarización internacional que ha tenido dicha determinación.
Serum concentrations of lgG, IgA and IgM were determined in 49 healthy university students, aged 18 to 25, by radial irnmunodiffusion, using commercially available plates. Results were compared to normal values re ported in the literature. It was found that lgG levels in our sample were slightly higher, whereas IgA and lgM levels were similar to those reported in other countries. A brief discussion of curr ent techniques for immunoglobulin quantitation is included, as well as some comments on international efforts to standardize this determination.
Serum concentrations of lgG, IgA and IgM were determined in 49 healthy university students, aged 18 to 25, by radial irnmunodiffusion, using commercially available plates. Results were compared to normal values re ported in the literature. It was found that lgG levels in our sample were slightly higher, whereas IgA and lgM levels were similar to those reported in other countries. A brief discussion of curr ent techniques for immunoglobulin quantitation is included, as well as some comments on international efforts to standardize this determination.
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inmunoglobulinas, valores de referencia, población de referencia
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