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Oxytetracycline and Gentamicin: Two Clinicallyrelevant Antimicrobials Widely Used by Costa Rican Farmers. Implications of Their Use Outside Clinical Cettings and Request for Action
dc.creator | Rodríguez Sánchez, César | |
dc.date.accessioned | 2015-05-18T19:16:32Z | |
dc.date.available | 2015-05-18T19:16:32Z | |
dc.date.issued | 2008-03-01 00:00:00 | |
dc.identifier.citation | http://revistas.ucr.ac.cr/index.php/medica/article/view/7848 | |
dc.identifier.uri | https://hdl.handle.net/10669/12365 | |
dc.description.abstract | This mini-review deals with oxytetracycline and gentamicin: two clinically-relevant antimicrobials that find extensive usage in horticulture and other productive activities. The manuscript begins with a few words on their mechanism of action and clinical utility. Thereafter I address the most important mechanisms of acquired or intrinsic resistance described to date and some implications of the unrestricted use of these drugs outside clinical settings. A number of reports on the occurrence of antimicrobial-resistance genes and antimicrobial-resistant bacteria in agroecosystems illustrates that a threat exists and justifies the plea for monitoring programs and environmental risk assessments with which the article concludes. | |
dc.description.abstract | Esta mini-revisión se relaciona con el uso de la oxitetraciclina y la gentamicina, dos antimicrobianos de aplicación en medicina humana, en la horticultura y otras actividades productivas. El manuscrito inicia con una breve descripción del mecanismo de acción y uso clínico de ambas drogas. Seguidamente, el autor aborda los principales mecanismos de resistencia adquirida que han sido descritos hasta la fecha y algunas implicaciones de su mal uso y abuso en escenarios no hospitalarios. En este sentido, sepresentan reportes de la ocurrencia de bacterias resistentes y genes de resistencia que demuestran la existencia de un riesgo y que justifican la instauración de programas de monitoreo y de impacto ambiental. | |
dc.relation.ispartof | Revista Médica de la Universidad de Costa Rica Vol. 2 Núm. 2 2008 | |
dc.title | Oxytetracycline and Gentamicin: Two Clinicallyrelevant Antimicrobials Widely Used by Costa Rican Farmers. Implications of Their Use Outside Clinical Cettings and Request for Action | |
dc.type | artículo original | |
dc.date.updated | 2015-05-18T19:16:32Z | |
dc.language.rfc3066 | en | |
dc.identifier.doi | 10.15517/rmu.v2i2.7848 |