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Predicting mortality with biomarkers: a population-based prospective cohort study for elderly Costa Ricans
(Population Health Metrics 10(1), 2012)
Background: Little is known about adult health and mortality relationships outside high-income nations, partly
because few datasets have contained biomarker data in representative populations. Our objective is to ...
Pulse blood pressure and cardiovascular mortality in a population-based cohort of elderly Costa Ricans
(2016-09)
We studied the relationships between blood pressure (BP), pulse pressure (PP) and cardiovascular (CV) death in older adults using data from 2346 participants enrolled in the Costa Rican CRELES study, mean age 76 years (s.d. ...
Predicting Survival from Telomere Length versus Conventional Predictors: A Multinational Population-Based Cohort Study
(2016-04)
Telomere length has generated substantial interest as a potential predictor of aging- related diseases and mortality. Some studies have reported significant associations, but few have tested its ability to discriminate ...
Stressors Over the Life Course and Neuroendocrine System Dysregulation in Costa Rica
(Journal of Aging and Health XX(X) 1–24, 2010-05-28)
Objectives: A key aspect of the increasingly popular allostatic load (AL) framework is that stressors experienced over the entire life course result in physiological dysregulation. Although core to AL theory, this idea has ...
Insurance and other socioeconomic determinants of elderly longevity in a Costa Rican panel
(Journal Biosocial science 37 705-720, 2005-11)
Official figures show that life expectancy in Costa Rica is longer than
in the United States (US), in spite of the fact that per capita health expenditure
is only one-tenth that of the US. To check whether this is for ...
Epigenome-Wide Association Study and Epigenetic Age Acceleration Associated with Cigarette Smoking among Costa Rican Adults
(2022-03-11)
Smoking-associated DNA methylation (DNAm) signatures are reproducible among studies of mostly European descent, with mixed evidence if smoking accelerates epigenetic aging and its relationship to longevity. We evaluated ...
The Nicoya region of Costa Rica: A high longevity island for elderly males
(Vienna Yearbook of Population Research, Vol 11, 2013-11)
Reliable data show that the Nicoyan region of Costa Rica is a hot spot of high
longevity. A survival follow-up of 16,300 elderly Costa Ricans estimated a Nicoya
death rate ratio (DRR) for males 1990–2011 of 0.80 (0.69–0.93 ...
Exploring why Costa Rica outperforms the United States in life expectancy: A tale of two inequality gradients
(2016)
Mortality in the United States is 18% higher than in Costa Rica among adult men and 10% higher among middle-aged women, despite the several times higher income and health expenditures of the United States. This comparison ...
Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region
(2017)
Background: The Nicoya Peninsula in Costa Rica has one of the highest old-age life expectancies in the world, but the underlying biological mechanisms of this longevity are not well understood. As DNA methylation is ...