ListarMicrobiología por tema "571.95 Toxicología"
Mostrando ítems 1-13 de 13
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Antivenomics: a proteomics tool for studying the immunoreactivity of antivenoms
(2015-03)Envenoming following snakebite is largely a neglected threat to public health in tropical and subtropical regions of Africa, Asia, Latin America and Oceania addicting some of the world’s poorest rural communities. An ... -
Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect
(2017-03-23)Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient’s lives. These are multi-mediated pathologies that ... -
Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles)
(2017-10)Pterois volitans/miles lionfish (adult and juvenile) dorsal spines and caudal fin extracts were compared in their general composition, enzymatic activities and hemolytic and cytotoxic effects on bovine aortic endothelial ... -
Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping
(2017-07)Snakebite antivenom is a 120 years old invention based on polyclonal mixtures of antibodies purified from the blood of hyper-immunized animals. Knowledge on antibody recognition sites (epitopes) on snake venom proteins ... -
Efectos locales en el envenenamiento ofídico en América Latina
(2003)Los envenenamientos por mordedura de serpiente constituyen un importante problema de salud pública en América Latina. La gran mayoría de estos envenenamientos son causados por mordeduras de serpientes de la familia Viperidae, ... -
Evaluation of the neutralizing ability of antivenoms for the treatment of snake bite envenoming in Central America
(1996)De nombreuses envenimations ophidiennes en Amérique centrale sont dues aux crotales (famille des Viperidae) parmi lesquels Bothrops asper est le principal responsable. Quelques accidents sont provoqués par les serpents ... -
Geographical variability of the venoms of four populations of Bothrops asper from Panama: Toxicological analysis and neutralization by a polyvalent antivenom
(2017-06)Bothrops asper is the medically most important venomous snake in Central America. In Panama, the country having the highest incidence of snakebites in Latin America, B. asper is widely distributed throughout the country ... -
Group-II phospholipase A2 enzymes
(2015-05)Phospholipase A2 are esterolytic enzymes that catalyze the hydrolysis of 1,2-diacyl-3-sn-glycerophospholipids at the C2 position, resulting in the formation of lysophospholipids and free fatty acid. They constitute one of ... -
Mecanismo de açao dos venenos de cobras corais
(2016)Os venenos apresentam um importante papel fisiológico para as serpentes: são os fatores responsáveis pela subjugação das presas, iniciam e auxiliam sua digestão e constituem um mecanismo de defesa contra predadores/agressores, ... -
Physicochemical characterization of Jicaro seeds (Crescentia alata H.B.K.): a novel protein-rich and oleaginous seed
(2017-03)Jicaro (Crescentia alata) is a tropical tree native to Mesoamerica well adapted to severe drought conditions. The seeds of the fruits were analyzed for protein, fatty acid, dietary fiber, phytate, polyphenol, tannin, ... -
Primary structures and partial toxicological characterization of two phospholipases A2 from Micrurus mipartitus and Micrurus dumerilii coral snake venoms
(2017-06)Snake venom phospholipases A2 (PLA2) share high sequence identities and a conserved structural scaffold, but show important functional differences. Only a few PLA2s have been purified and characterized from coral snake ... -
Proteomic analysis of venom variability and ontogeny across the arboreal palm-pitvipers (genus Bothriechis)
(2017-01)Bothriechis is a genus of eleven currently recognized slender and arboreal venomous snakes, commonly called palm-pitvipers that range from southern Mexico to northern South America. Despite dietary studies suggesting that ... -
Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms
(2017-04)This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achieving a more ...