Browsing Farmacia by Author "Vargas Zúñiga, Rolando"
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Analysis and Characterization of Quality Systems in the Natural Medicinal Products Industry in Costa Rica and the world.
Hernández Jiménez, Natalia; Ortuño Montero, Natalia; Rojas Salas, María Fernanda; Chavarría Rojas, Marianela; Vargas Zúñiga, Rolando; Madrigal Redondo, German Leonardo (2021-12)The use of natural products has been a practice carried out by people throughout history to take care of their health and to alleviate a wide variety of ailments. The reasons for the use of natural medicine at this time, ... -
Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate
Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2018)It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ... -
Comparison of the antifungal and antibacterial effect of the essential oil and ethanolic extract of the Zingiber officinale Rhizome (Ginger) cultivated in the San Carlos zone, Costa Rica in order to standardize a hydroponic medicinal cultivation of the same
González Guevara, Jean Carlo; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Rodríguez Sibaja, Santiago (2020)Introduction: Ginger is a medicinal plant native to India. Its potential use in cosmetics, medicines and natural products has been reported, however depending on the conditions of cultivation the medicinal components of ... -
Design of experiments assessment for the determination of moisture content in five herbal raw materials contained in tea products
Castillo Henríquez, Luis; Baltodano Viales, Eleaneth; Ramírez Arguedas, Nils Antonio; Vargas Zúñiga, Rolando; Hanley, Georgia (2020-02)Research interest in natural raw materials is rapidly growing due to the high demand for natural products like herbal teas. Their quality control has a direct impact on safety and efficacy. The aim of this study was to ... -
Design of Experiments for the Establishment of the Dissolution Test Conditions of Rupatadine Fumarate 10 mg tablets
Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2019)Design of Experiments (DoE) is a statistical model that aims to determine if the factors under study affect the response, and if so, it determines the conditions under which this variable of interest can be optimized. In ... -
Determination of the Impact Caused by Direct Compression on the Crystalline State of Rupatadine Fumarate 10 mg Tablets
Castillo Henríquez, Luis; Vargas Zúñiga, Rolando; Madrigal Redondo, German; Carazo Berrocal, Gustavo; Hanley Vargas, Georgia (2019-11-08)The aim of this study is to determine the impact caused by direct compression on the crystalline state of two prototypes of Rupatadine fumarate 10 mg tablets. The tablets were manufactured through direct compression. ... -
Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach
Castillo Henríquez, Luis; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Madrigal Redondo, German; Calvo Guzmán, Briner; Baltodano Viales, Eleaneth (2019)The main objective of this research is to develop an immediate release Rupatadine fumarate 10 mg tablets formulation by direct compression, through a Quality by Design approach in Costa Rica. Methods: According to a ... -
Effect of preservative in the physicochemical stability of cosmetic products based on natural resources from Costa Rican flora
Vargas Zúñiga, Rolando; Madrigal Redondo, German (2015)A problem of rural women in Latin America is the poor access to economic resources; a solution we propose is to implement a collaborative model, where are used natural resources in the area for production ... -
Equivalencia terapéutica de tabletas de levofloxacino del mercado costarricense por comparación de perfiles de disolución
Ramírez Arguedas, Nils Antonio; González Mora, Esteban; Fonseca González, Lidiette; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Baudrit Carrillo, Olga (2012-10)El presente trabajo corresponde a un estudio in vitro de equivalencia terapéutica e intercambiabilidad de tres medicamentos multiorigen de tabletas de liberación inmediata de levofloxacino del mercado ... -
Evaluación del poder antioxidante, propiedades fisicoquímicas y composición fitoquimica de extractos de semilla de bactris gasipaes para formulaciones dermocosméticas
Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio; Baltodano Viales, Eleaneth; Blanco Barrantes, Jeimy; Loría Gutiérrez, Arlene (2019)Bactris gasipaes es una palmera de la cual se obtiene una fruta conocida comúnmente en Costa Rica como Pejibaye, es autóctona de América Central, muy común en la alimentación de Costa Rica, por su alto contenido de almidón ... -
Ginsenosides and other Phytochemicals of Panax spp. Properties and uses in the pharmaceutical field
Solís Vindas, Gretel; Chavarría Rojas, Marianela; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Madrigal Redondo, German (2021)Introduction: Ginseng has been used since ancient times, for its medicinal properties. This plant comes from the genus Panax, and the most representative species are Panax quinquefolium, Panax ginseng, and Panax ... -
Identificación de dos formas polimórficas cristalinas de clopidogrel bisulfato en materia prima farmacéutica
Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio (2014)Introducción: el clopidogrel bisulfato existe en numerosas formas cristalinas, que varían en su estabilidad fisicoquímica, por lo que algunas de estas formas, patentadas o no, son útiles en la fabricación de medicamentos. ... -
Identification of etoricoxib polymorphic crystalline form in pharmaceutical raw materials
Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio (2017)The determination of the spatial configuration of the compounds structures used in the production of drugs is of utmost importance due to the different physical characteristics that each have in their solid state and ... -
Identification of rupatadine fumarate polymorphic crystalline forms in pharmaceutical raw materials
Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2018)Polymorphism analysis of pharmaceutical raw materials is considered one of the most relevant evaluations that should be done. As we know, different crystal forms from the same molecule have differences in terms of their ... -
Identification of solid phase state of hemi-dihydrate atorvastatin in pharmaceutical raw materials
Madrigal Redondo, German; Carazo Berrocal, Gustavo; Vargas Zúñiga, Rolando; Ramírez Arguedas, Nils Antonio (2015)Determining the spatial configuration of the structures of compounds used in the production of medicines is extremely important due to the different characteristics of each of them in its solid ... -
Innovación en la producción microempresaria de cosméticos de leche de cabra en la universidad de Costa Rica
Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio (2015)Desde el año 2009 la Universidad de Costa Rica por medio de la Facultad de Farmacia se ha dedicado a promover un modelo de desarrollo en la pequeña y mediana industria cosmética, para las zonas rurales o más pobres de Costa ... -
Innovation in the production of a cream based on thermal waters from the surroundigs of the Arenal Volcano in Costa Rica
Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio (2015)Introduction: Since 2009 the University of Costa Rica, through the Faculty of Pharmacy, is dedicated to promote a model of development in cosmetics in small and medium industries in rural or poorest areas of Costa Rica, ... -
Multi-vesicular phosphatidylcholine liposomes as vehicles for curcumin in a nutritious drinkable formulation
Madrigal Redondo, German; Vargas Zúñiga, Rolando; Chavarría Rojas, Marianela; Sibaja Rodríguez, Santiago; Chaves Noguera, Sindy (2017)Liposomal vesicles are used as a strategy to enhance the stability and bioavailability of its bioactive components. Large part of its characteristics can be attributed to the likeness between the liposomal and biological ... -
Nueva estrategia didáctica y su evaluación por parte de los estudiantes del curso fisicoquímica farmacéutica
Vargas Zúñiga, Rolando; Madrigal Redondo, German; Ramírez Arguedas, Nils Antonio (2012-10)El curso de Fisicoquímica Farmacéutica II, que se imparte en la Facultad de Farmacia de la Universidad de Costa Rica, es uno de los más complicados para el desarrollo de los aprendizajes ... -
Physicochemical Characterization of a Liposomal Formulation Based on Glucosamine and Vitamin D, Commercialized as a Nutritional Supplement
Madrigal Redondo, German; Vargas Zúñiga, Rolando; Chavarría Rojas, Marianela; Sibaja Rodríguez, Santiago; Chaves Noguera, Sindy (2018)In the last years, the transport and release mechanism of bioactive compounds has been studied. The liposomes are multivesicular systems that enhance the absorption, stability, and transport of these compounds. The ...