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Mostrando ítems 21-30 de 44
Empleo de técnicas y materiales biológicos en la búsqueda de productos activos contra la malaria
(2001)
Se describen los métodos empleados en el estudio del efecto de extractos de insectos preparados en el Instituto Nacional de Biodiversidad de Costa Rica, sobre un tipo de malaria murina producida por el Plasmodium bergheim. ...
Bioactivity of prenylated hydroxybenzoic acids from Piper garagaranum C. DC
(2022)
A bio-assay guided fractionation of Piper garagaranum C. DC. led to the isolation of two prenylated hydroxybenzoic
acids (1-2) with anti-inflammatory and cytotoxic activities. The anti-inflammatory action was determined
in ...
Diterpenes from Fleischmannia hymenophylla and Brickellia laciniata
(1989)
The aerial parts of Fleischmannia hymenolepis gave in addition to phytol and sesamin a new derivative of beyerene named hymenophylloide. The aerial parts of Brickellia laciniata afforded several new labdane derivatives and ...
Germacranolides and other constituents from ageratzna species
(1988)
The aerial parts of Ageratina anisochroma gave several thymol derivatives including five new ones, a hydroxypiperitol glucoside, some substituted benzyl benzoates and several germacranolides related to provincialin. From ...
Estudio de propóleos a base de nemorosona: Composición química y Estabilidad
(2022)
Los propóleos poseen un alto valor etnofarmacológico, conocido por la humanidad desde hace milenios. Su variabilidad química hace difícil tanto su estudio cómo su caracterización. En este trabajo se caracterizó el perfil ...
Identification of Protein Kinase C Activation as a Novel Mechanism for RGS2 Protein Upregulation through Phenotypic Screening of Natural Product Extracts
(2014)
Biochemical high-throughput screening is widely used in drug discovery, using a variety of small molecule libraries. However, broader screening strategies may be more beneficial to identify novel biologic mechanisms. In ...
Titration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase Inhibitors
(2011)
The chemical diversity of nature has tremendous potential for the discovery of molecular probes and medicinal agents. However, sensitivity of HTS assays to interfering components of crude extracts derived from plants, and ...
Isolation of Major Components from the Roots of Godmania aesculifolia and Determination of Their Antifungal Activities
(2013)
From the methanol root extract of Godmania aesculifolia, a species selected in a multinational OAS program aimed at discovering antifungal compounds from Latin American plants, a new chavicol diglycoside (1), the known ...
Heliangolides from Viguiera sylvatica
(1989)
The extract of the aerial parts of Viguiera sylvatica gave, in addition to known heliangolides, four new heliangolides related to 1-desoxyniveusin A and one to 11,13-dihydrofuroheliangolide as well as three guaianolides, ...
Oral administration of Costa Rican guava (Psidium friedrichsthalianum) juice induces changes in urinary excretion of energy-related compounds in Wistar rats determined by 1H NMR
(2020-08)
Introduction: Psidium friedrichsthalianum fruits have in vitro antioxidant activity and their intake has been suggested to have potential health benefits; however, there is still no evidence on the potential in vivo effect ...