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Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach

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Monitoring occurrence of SARS-CoV-2 in school populations A wastewater-based approach - journal.pone.0270168.pdf (1.394Mb)
Date
2022-06-17
Author
Castro Gutiérrez, Víctor Manuel
Hassard, Francis
Vu, Milan
Leitão, Rodrigo
Burczynska, Beata
Wildeboer, Dirk
Stanton, Isobel
Rahimzadeh, Shadi
Baio, Gianluca
Garelick, Hemda
Hofman, Jan
Kasprzyck Hordern, Barbara
Kwiatkowska, Rachel
Majeed, Azeem
Priest, Sally
Grimsley, Jasmine
Lundy, Lian
Singer, Andrew C.
Di Cesare, Mariachiara
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Abstract
Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.
URI
https://hdl.handle.net/10669/87553
External link to the item
10.1371/journal.pone.0270168
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0270168
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