Mechanical ventilator development during COVID-19 crisis: Preclinical data analysis from porcine bio-model

dc.creatorConejo Rodríguez, Elian
dc.creatorAraya Jiménez, Carlos Andrés
dc.creatorCalderón Obaldía, Eduardo
dc.creatorGarcía Vindas, José Ralph
dc.date.accessioned2025-02-03T18:20:18Z
dc.date.available2025-02-03T18:20:18Z
dc.date.issued2024-10-31
dc.description.abstractThis paper describes a mechanical ventilator prototype with preclinical test performed on 10 bioporcine models, where tests were performed for eight hours for each individuals, giving the respective life support on different scenarios inducing stress and evaluating that each subject physiological parameters remain and return swiftly to the normal values. The results have shown the capabilities to maintain physiological parameters for each subject under test and present also the capability of monitoring the pulmonary parameter, compliance (C), computed from the pressure-volume hysteresis loop measured by the prototype, so that this is the unique proposed prototype to present this capability at this extended subject samples. The ventilator prototype was designed following the Medicine & Healthcare products Regulatory Agency (MHRA) from United Kingdom (UK), that was the first guidelines for manufactured ventilator system in the pandemic of COVID-19 emergency. Finally the components used in the mechanical ventilator comes from different industrial applications, that its performances were tested for years and its supply were no affected by the surge of the acquisition of critical electro-mechanical components used by the commercial ventilator factories under pandemic situation as COVID-19 pandemic.
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigación en Ciencias Atómicas Nucleares y Moleculares (CICANUM)
dc.description.procedenceUCR::Vicerrectoría de Docencia::Ciencias Básicas::Facultad de Ciencias::Escuela de Física
dc.description.procedenceUCR::Vicerrectoría de Docencia::Ingeniería::Facultad de Ingeniería::Escuela de Ingeniería Eléctrica
dc.description.procedenceUCR::Vicerrectoría de Docencia::Ingeniería::Facultad de Ingeniería::Escuela de Ingeniería Mecánica
dc.description.sponsorshipUniversidad de Costa Rica/[]/UCR/Costa Rica
dc.description.sponsorshipMinisterio de Ciencia, Innovación, Tecnología, y Telecomunicaciones/[]/MICITT/Costa Rica
dc.identifier.doihttps://doi.org/10.11648/j.wjph.20240904.13
dc.identifier.issn2637-6040
dc.identifier.issn2637-6059
dc.identifier.urihttps://hdl.handle.net/10669/101629
dc.language.isoeng
dc.relation.ispartofseries9; 4
dc.rightsacceso abierto
dc.sourceWorld Journal of Public Health, 9(4), 335-342
dc.subjectcompliance
dc.subjectCOVID-19
dc.subjectmechanical ventilator
dc.subjectpressure-volume hysteresis loop
dc.subjectporcine bio-model
dc.subjectpreclinical data
dc.titleMechanical ventilator development during COVID-19 crisis: Preclinical data analysis from porcine bio-model
dc.typeartículo original

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