Frecuencia de marcadores serológicos del virus de la hepatitis B en sujetos fallecidos en un Hospital clase A de San José
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San Gil Caballero, Enrique
Mata Jiménez, Leonardo
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Abstract
Objetivo: Conocer la frecuencia de tres marcadores serológicos del virus de la hepatitis B (VHB): antígeno de superficie (HBsAg), anticuerpos anti-antígeno de superficie (anti-HBs) y anticuerpos totales al antígeno central (anti-HBc) en una población de adultos fallecidos en un hospital general. Material y Métodos: Mediante las técnicas de ELISA y RIA se hizo determinación de la presencia de tres marcadores del VHB en el suero de 336 pacientes fallecidos. Resultados: Se encontró HBsAg en el 2,4% de los casos; anticuerpos anti-HBs en el 29,8%; y anti-HBc en el 31,8%. Conclusiones La frecuencia de los tres marcadores mencionados fue más alta en este casuística, que en otras de personas vivas del país descritas por otros autores(1-3). Los autores no pudieron ubicar investigaciones similares a esta, en personas hospitalizadas que mueren en nosocomios. Este estudio sugiere que la infección con HBV es más frecuente en la población hospitalizada que muere en el hospital, que en la población general.
Objective: To determine the frequency of three serological markers of Hepatitis B virus (HBV) in a series of corpses in a Class A general hospital of Costa Rica Material and Methods: Using ELISA and RIA methods, three serological markers of HBV were investigated in the serum of the corpses. Results: HBsAg was found in 2.4% of the deceased, anti-HBs in 29.8%; and anti- HBc in 31.8%. Conclusions: The frequency of the markers studied was relatively high in this study, in comparison with rates in blood donors and other population groups in the country. Similar studies of hospitalized deceased persons were not found in the world literature. The present study suggests that infection with HBV is more common in nosocomial populations.
Objective: To determine the frequency of three serological markers of Hepatitis B virus (HBV) in a series of corpses in a Class A general hospital of Costa Rica Material and Methods: Using ELISA and RIA methods, three serological markers of HBV were investigated in the serum of the corpses. Results: HBsAg was found in 2.4% of the deceased, anti-HBs in 29.8%; and anti- HBc in 31.8%. Conclusions: The frequency of the markers studied was relatively high in this study, in comparison with rates in blood donors and other population groups in the country. Similar studies of hospitalized deceased persons were not found in the world literature. The present study suggests that infection with HBV is more common in nosocomial populations.
Description
Artículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 1996
Keywords
Costa Rica, Decesos hospitalarios, Salud pública