Listar Microbiología por título
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Effects of a myotoxic phospholipase A2 isolated from Bothrops asper venom on skeletal muscle sarcoplasmic reticulum
(1987)The myotoxin from B. asper snake venom inhibited Ca-ATPase activity of rabbit sarcoplasmic reticulum after incubation in vitro. Inhibition was non-competitive and albumin enhanced the effect of the toxin. Furthermore, B. ... -
Effects of Bothrops asper (terciopelo) myotoxin III, a basic phospholipase A2, on liposomes and mouse gastrocnemius muscle
(1993-02)The action of Bothrops asper myotoxin III, a basic phospholipase A2 which induces acute muscle damage, was studied in mouse gastrocnemius muscle in vivo and in vitro and in multilamellar liposomes. Myonecrosis occurred ... -
Effects of Bothrops asper snake venom on lymphatic vessels: insights into a hidden aspect of envenomation
(PlosOne 2(10):e318, 2008-10-15)Background: Envenomations by the snake Bothrops asper represent a serious medical problem in Central America and parts of South America. These envenomations concur with drastic local tissue pathology, including a prominent ... -
Effects of Bothrops asper snake venom on the expression of cyclooxygenases and production of prostaglandins by peritoneal leukocytes in vivo, and by isolated neutrophils and macrophages in vitro
(2009-03)In this study, the ability of Bothrops asper snake venom (BaV) to increase the production of prostaglandins PGE2 and PGD2 was assessed in a mouse model in vivo and in inflammatory cells in vitro. In addition, the expressions ... -
Effects of chemical modifications of crotoxin B, the phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom, on its enzymatic and pharmacological activities
(2001-09-01)Crotoxin B, the basic Asp49-PLA2 subunit from crotoxin, the main component of Crotalus durissus terrificus venom, displays myotoxic, edema-inducing, bactericidal (upon Escherichia coli), liposomal-disrupting and anticoagulant ... -
Effects of neutrophil depletion in the local pathological alterations and muscle regeneration in mice injected with Bothrops jararaca snake venom
(2005-04)In order to study the role of neutrophils in the acute local pathological alterations induced by Bothrops jararaca snake venom, and in the process of skeletal muscle regeneration that follows, an experimental model was ... -
Effects of oxytetracycline on the performance and activity of biomixtures: Removal of herbicides and mineralization of chlorpyrifos
(2017)Biopurification systems (BPS) are design to remove pesticides from agricultural wastewater. This work assays for the first time the potential effect of an antibiotic of agricultural use (oxytetracycline, OTC) on the ... -
Effects on cultured mammalian cells of myotoxin III, a phospholipase A2 isolated from Bothrops asper (terciopelo) venom
(1993-11)Myotoxin III (MT-III), a myotoxic phospholipase A2 from Bothrops asper, was studied with respect to interactions with cultured mammalian cells and red blood cells. Tests of the cytopathogenic effect of MT-III on different ... -
Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without β-propiolactone, in the treatment of Bothrops asper bites in Colombia
(2006-12)The efficacy and safety of two whole IgG polyvalent antivenoms (A and B) were compared in a randomised, blinded clinical trial in 67 patients systemically envenomed by Bothrops asper in Colombia. Both antivenoms were ... -
Efficacy of IgG and F(ab′)2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate
(2012)Proteomic analysis of wound exudates represents a valuable tool to investigate tissue pathology and to assess the therapeutic success of various interventions. In this study, the ability of horse-derived IgG and F(ab0)2 ... -
Elaboración de un plan piloto para la implementación de un modelo de gestión de calidad basado en procesos en la sede de Santa Ana del Hospital Clínica Bíblica
(2023-07-25)El presente trabajo pretende la creación de un plan piloto en formato DMAIC para la migración del Sistema de Gestión de Calidad actual a un sistema de gestión basado en procesos en el Laboratorio Clínico de la sede de Santa ... -
Elapid venom toxins: multiple recruitments of ancient scaffolds
(1999-01)Nigroxins A and B, two myotoxic phospholipases A2 (PLA2s) from the venom of the American elapid Micrurus nigrocinctus, belong to a new PLA2 subclass. Their primary structures were established and compared with those of ... -
Electrophoretic and immunochemical studies of Micrurus venoms
(1994)The electrophoretic mobilities of venom components from 15 Micrurus species were studied by polyacrylamide gel electrophoresis. The venoms showed species-specific protein patterns under native (PAGE) or denaturing (urea-PAGE) ... -
Elimination of fungicides in biopurification systems: Effect of fungal bioaugmentation on removal performance and microbial community structure
(2017-11)Bioaugmentation with ligninolytic fungi represents a potential way to improve the performance of biomixtures used in biopurification systems for the treatment of pesticide-containing agricultural wastewater. The fungus ... -
Elucidating Spirocerca lupi spread in the Americas by using phylogenetic and phylogeographic analyses
(2023)Spirocerca lupi is a parasitic nematode of domestic and wild canids of the world. This nematode induces esophageal spirocercosis and may eventually lead to carcinomas, aortic aneurisms, and death of the animal. Two genotypes ... -
Emergence of an Outbreak-Associated Clostridium difficile Variant with Increased Virulence
(2015-04)The prevalence of Clostridium difficile infections has increased due to the emergence of epidemic variants from diverse genetic lineages. Here we describe the emergence of a novel variant during an outbreak in a Costa Rican ... -
Emergence of Clostridium difficile NAP1 in Latin America
(2010-02)The NAP1 and NAP2 strains of Clostridium difficile have been linked to nosocomial outbreaks of antibiotic-associated diarrhea (AAD) and pseudomembranous colitis in North American and European countries (4, 5). We found ... -
Ending the drought: New strategies for improving the flow of affordable, effective antivenoms in Asia and Africa
(2011-08-24)The development of snake antivenoms more than a century ago should have heralded effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural populations around the world. That snakebite still ... -
Enfermedad de Chagas en Costa Rica: Estudio comparativo en dos épocas diferentes
(2006)Para actualizar la situación de la Enfermedad de Chagas en Costa Rica se realizó un estudio serológico y epidemiológico parcial en 4 zonas de riesgo en el país. Un total de 1.561 estudiantes de 6 a 12 años fueron estudiados ...