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SDS‑induced hexameric oligomerization of myotoxin‑II from Bothrops asper assessed by sedimentation velocity and nuclear magnetic resonance
(2023)
We report the solution behavior, oligomerization state, and structural details of myotoxin-II purified from the venom of
Bothrops asper in the presence and absence of sodium dodecyl sulfate (SDS) and multiple lipids, as ...
Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing
(BMC Genomics, 12:259, 2011, 2011)
Background: A long term research goal of venomics, of applied importance for improving current antivenom
therapy, but also for drug discovery, is to understand the pharmacological potential of venoms. Individually ...
CMV-encoded Fcγ receptors: modulators at the interface of innate and adaptive immunity
(2014-10-07)
The constant region of IgG antibodies mediates antiviral activities upon engaging host Fcγ receptors (FcγRs) expressed by a variety of immune cells, such as antibody-dependent cellullar cytotoxcity (ADCC) executed by natural ...
Arboviral encephalitis in Costa Rican horses: 2009-2016
(2016-12)
Arbovirus of the genus Alphavirus and Flavivirus
can cause febrile illness and sometimes neurological disease
in both humans and animals. West Nile Virus (WNV), Eastern
Equine Encephalitis Virus (EEEV), Western Equine ...
Fluorescence Imaging Approaches in Flavivirus Research
(2021-10-01)
The genus Flavivirus within the family Flaviviridae contains many
arthropod-borne infectious agents of medical relevance like dengue virus (DENV),
Zika virus (ZIKV), and West Nile virus (WNV), among others, that cause ...
Resistencia de Aedes Aegypti (Diptera: Culicidae) a insecticidas organofosforados y piretroides en la localidad de Orotina, Alajuela, Costa Rica
Resistance of Aedes aegypti (Diptera: Culicidae) to organophosphate and pyrethroid insecticides in Orotina, Alajuela, Costa Rica
(2019)
Objetivos: Determinar la resistencia de una cepa de Aedes.
aegypti de Orotina a insecticidas organofosforados (temefós y
malatión), y a piretroides (deltametrina, lambda cialotrina y
cipermetrina).
Métodos: La evaluación ...
Removal of pharmaceuticals, polybrominated flame retardants and UV-filters from sludge by the fungus Trametes versicolor in bioslurry reactor
(2012-09)
Conventional wastewater treatments are inefficient in the removal of many organic pollutants. The pres ence of these contaminants in the final sludge represents a source of environmental pollution due to the
increasing ...
Simultaneous removal of structurally different pesticides in a biomixture: Detoxification and effect of oxytetracycline
(2017-02)
The biopurification systems (BPS) used for the treatment of pesticide-containing wastewater must present a versatile degrading ability, in order to remove different active ingredients according to the crop protection ...
Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors
(2019)
Clostridium difficile induces antibiotic-associated diarrhea due to the release of toxin A (TcdA) and toxin B (TcdB), the latter being its main virulence factor. The epidemic strain NAP1/027 has an increased virulence ...
Situación actual de la Leucemia Aguda de Linaje Ambiguo: Una revisión sistemática
(2021-08)
La leucemia aguda es un cáncer hematopoyético en la cual prolifera una población de células malignas llamadas blastos, que comprometen más del 20% del componente celular de la médula ósea. La gran mayoría de estas pueden ...